Journal article
The basic chemistry of nitrogen monoxide and peroxynitrite.
- Koppenol WH Laboratorium für Anorganische Chemie, Eidgenössische Technische Hochschule, Zürich, Switzerland. koppenol@inorg.chem.ethz.ch
- 1998-09-19
Published in:
- Free radical biology & medicine. - 1998
Chemical Phenomena
Chemistry, Physical
Diffusion
Nitrates
Nitric Oxide
Oxidation-Reduction
Solubility
Superoxide Dismutase
Thermodynamics
English
After a discussion of the physical chemistry of nitrogen monoxide, such as solubility (1.55 mM at 37 degrees C and an ionic strength of 0.15 M) and diffusion constant (4.8 x 10(-5) cm2s(-1)), several reactions that can acts as sinks are discussed, namely the reaction with dioxygen, with thiols and with superoxide. Of these, the latter reaction leads to a powerful oxidant, peroxynitrite. The thermodynamic and kinetic properties of this molecule are also reviewed.
- Language
-
- English
- Open access status
- closed
- Identifiers
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- DOI 10.1016/s0891-5849(98)00093-8
- PMID 9741577
- Persistent URL
- https://sonar.ch/global/documents/52468
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