Gadodiamide as an Alternative Contrast Agent during Angioplasty in Patients with Contraindications to Iodinated Media

Zeller, Thomas; Müller, Christian; Frank, Ulrich; Bürgelin, Karlheinz; Sinn, Lutz; Horn, Barbara; Flügel, Peter C.; Roskamm, Helmut

doi:10.1177/152660280200900514

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Gadodiamide as an Alternative Contrast Agent during Angioplasty in Patients with Contraindications to Iodinated Media

Zeller, Thomas Department of Angiology, Herz-Zentrum Bad Krozingen
Müller, Christian Department of Internal Medicine, University Hospital, Basel, Switzerland
Frank, Ulrich Department of Angiology, Herz-Zentrum Bad Krozingen
Bürgelin, Karlheinz Department of Angiology, Herz-Zentrum Bad Krozingen
Sinn, Lutz Department of Angiology, Herz-Zentrum Bad Krozingen
Horn, Barbara Department of Angiology, Herz-Zentrum Bad Krozingen
Flügel, Peter C. Department of Radiology, St. Josephs Hospital, Freiburg, Germany
Roskamm, Helmut Department of Angiology, Herz-Zentrum Bad Krozingen

2016-6-24

Published in:

Journal of Endovascular Therapy. - SAGE Publications. - 2002, vol. 9, no. 5, p. 625-632

Radiology Nuclear Medicine and imaging

Cardiology and Cardiovascular Medicine

English Purpose: To evaluate gadodiamide as an alternative contrast agent for peripheral and renal angioplasty in patients with contraindications to iodinated contrast media. Methods: Seventeen patients (10 men; mean age 74 years, range 68–83) with contraindication to iodinated contrast media were given gadodiamide as the contrast agent during peripheral and renal intra-arterial digital subtraction angiography (DSA) and subsequent percutaneous interventions (balloon angioplasty, stent placement). Results: The mean volume of gadodiamide used was 136 ± 46 mL (range 60–200). No serious side effects were observed, especially no change in renal or thyroid function; no exanthema or other allergic reactions were noted. In patients without renal artery intervention, serum creatinine at discharge remained unchanged (2.57 ± 1.43 mg/dL to 2.40 ± 1.28 mg/dL, p=NS). In patients undergoing angioplasty/stenting of renal artery stenoses, serum creatinine decreased significantly from 3.53 ± 1.75 mg/dL to 2.36 ± 1.15 mg/dL (p<0.01). All but 1 intervention was successful. Using a simple scoring system, 2 judges blinded to the contrast agent graded the quality of the peripheral DSAs as “good,” whereas renal DSA images were only “sufficient.” Conclusions: For patients with contraindications to iodinated materials, gadodiamide may be a suitable alternative for renal or peripheral DSA followed by angioplasty.

Language

English

Open access status

closed

Identifiers

DOI 10.1177/152660280200900514
ISSN 1526-6028

Persistent URL

https://sonar.ch/global/documents/5567

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