Journal article

The genetic architecture of the human cerebral cortex

  • Grasby, Katrina L. ORCID Psychiatric Genetics, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
  • Jahanshad, Neda ORCID Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA.
  • Painter, Jodie N. ORCID Psychiatric Genetics, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
  • Colodro-Conde, Lucía ORCID Faculty of Psychology, University of Murcia, Murcia, Spain.
  • Bralten, Janita ORCID Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, Netherlands.
  • Hibar, Derrek P. Personalized Healthcare, Genentech, Inc., South San Francisco, CA, USA.
  • Lind, Penelope A. ORCID Faculty of Medicine, University of Queensland, Brisbane, QLD, Australia.
  • Pizzagalli, Fabrizio Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA.
  • Ching, Christopher R. K. Graduate Interdepartmental Program in Neuroscience, University of California Los Angeles, Los Angeles, CA, USA.
  • McMahon, Mary Agnes B. ORCID Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA.
  • Shatokhina, Natalia Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA.
  • Zsembik, Leo C. P. ORCID Department of Genetics and UNC Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Thomopoulos, Sophia I. Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA.
  • Zhu, Alyssa H. ORCID Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA.
  • Strike, Lachlan T. ORCID Queensland Brain Institute, University of Queensland, St Lucia, QLD, Australia.
  • Agartz, Ingrid ORCID Centre for Psychiatric Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
  • Alhusaini, Saud Neurology Department, Yale School of Medicine, New Haven, CT, USA.
  • Almeida, Marcio A. A. ORCID Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA.
  • Alnæs, Dag NORMENT - K.G. Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Amlien, Inge K. ORCID Centre for Lifespan Changes in Brain and Cognition, Department of Psychology, University of Oslo, Oslo, Norway.
  • Andersson, Micael ORCID Umeå Center for Functional Brain Imaging, Umeå University, Umeå, Sweden.
  • Ard, Tyler ORCID Laboratory of Neuro Imaging, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
  • Armstrong, Nicola J. ORCID Mathematics and Statistics, Murdoch University, Murdoch, WA, Australia.
  • Ashley-Koch, Allison Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA.
  • Atkins, Joshua R. ORCID Priority Centre for Brain and Mental Health Research, University of Newcastle, Callaghan, NSW, Australia.
  • Bernard, Manon ORCID The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.
  • Brouwer, Rachel M. ORCID Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
  • Buimer, Elizabeth E. L. ORCID Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
  • Bülow, Robin Institute for Radiology and Neuroradiology, University Medicine, Ernst-Moritz-Arndt University, Greifswald, Germany.
  • Bürger, Christian Department of Psychiatry, University of Münster, Münster, Germany.
  • Cannon, Dara M. Centre for Neuroimaging and Cognitive Genomics, National University of Ireland Galway, Galway, Ireland.
  • Chakravarty, Mallar Departments of Psychiatry and Biological and Biomedical Engineering, McGill University, Montreal, QC, Canada.
  • Chen, Qiang ORCID Lieber Institute for Brain Development, Baltimore, MD, USA.
  • Cheung, Joshua W. ORCID Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA.
  • Couvy-Duchesne, Baptiste ORCID Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
  • Dale, Anders M. ORCID Department of Radiology, University of California San Diego, San Diego, CA, USA.
  • Dalvie, Shareefa Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa.
  • de Araujo, Tânia K. ORCID BRAINN - Brazilian Institute of Neuroscience and Neurotechnology, Campinas, Brazil.
  • de Zubicaray, Greig I. ORCID Faculty of Health, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, QLD, Australia.
  • de Zwarte, Sonja M. C. Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
  • den Braber, Anouk Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, Netherlands.
  • Doan, Nhat Trung NORMENT - K.G. Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Dohm, Katharina ORCID Department of Psychiatry, University of Münster, Münster, Germany.
  • Ehrlich, Stefan ORCID Division of Psychological and Social Medicine and Developmental Neurosciences, Faculty of Medicine, Technische Universität Dresden, Dresden, Germany.
  • Engelbrecht, Hannah-Ruth ORCID Division of Human Genetics, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.
  • Erk, Susanne Division of Mind and Brain Research, Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charité - Universitätsmedizin Berlin corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
  • Fan, Chun Chieh Department of Cognitive Science, University of California San Diego, San Diego, CA, USA.
  • Fedko, Iryna O. ORCID Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
  • Foley, Sonya F. Cardiff University Brain Research Imaging Centre, Cardiff University, Cardiff, UK.
  • Ford, Judith M. ORCID San Francisco Veterans Administration Medical Center, San Francisco, CA, USA.
  • Fukunaga, Masaki ORCID Division of Cerebral Integration, National Institute for Physiological Sciences, Okazaki, Japan.
  • Garrett, Melanie E. ORCID Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA.
  • Ge, Tian Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, MA, USA.
  • Giddaluru, Sudheer NORMENT - K.G. Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway.
  • Goldman, Aaron L. Lieber Institute for Brain Development, Baltimore, MD, USA.
  • Green, Melissa J. ORCID Neuroscience Research Australia, Sydney, NSW, Australia.
  • Groenewold, Nynke A. Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa.
  • Grotegerd, Dominik ORCID Department of Psychiatry, University of Münster, Münster, Germany.
  • Gurholt, Tiril P. ORCID Department of Psychiatric Research, Diakonhjemmet Hospital, Oslo, Norway.
  • Gutman, Boris A. ORCID Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, IL, USA.
  • Hansell, Narelle K. ORCID Queensland Brain Institute, University of Queensland, St Lucia, QLD, Australia.
  • Harris, Mathew A. ORCID Division of Psychiatry, University of Edinburgh, Edinburgh, UK.
  • Harrison, Marc B. ORCID Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA.
  • Haswell, Courtney C. ORCID Mental Illness Research Education and Clinical Center for Post Deployment Mental Health, Durham VA Medical Center, Durham, NC, USA.
  • Hauser, Michael ORCID Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA.
  • Herms, Stefan ORCID Department of Genomics, Life & Brain Research Center, University of Bonn, Bonn, Germany.
  • Heslenfeld, Dirk J. Department of Cognitive and Clinical Neuropsychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
  • Ho, New Fei Research Division, Institute of Mental Health, Singapore, Singapore.
  • Hoehn, David ORCID Max Planck Institute of Psychiatry, Munich, Germany.
  • Hoffmann, Per ORCID Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany.
  • Holleran, Laurena ORCID Centre for Neuroimaging and Cognitive Genomics, School of Psychology, National University of Ireland Galway, Galway, Ireland.
  • Hoogman, Martine ORCID Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, Netherlands.
  • Hottenga, Jouke-Jan ORCID Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
  • Ikeda, Masashi ORCID Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Japan.
  • Janowitz, Deborah ORCID Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.
  • Jansen, Iris E. ORCID Department of Neurology, Alzheimer Center, Amsterdam Neuroscience, Vrije Universiteit Medical Center, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
  • Jia, Tianye ORCID Centre for Population Neuroscience and Precision Medicine (PONS), Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, UK.
  • Jockwitz, Christiane ORCID JARA-BRAIN, Jülich-Aachen Research Alliance, Jülich, Germany.
  • Kanai, Ryota ORCID Earth-Life Science Institute, Tokyo Institute of Technology, Tokyo, Japan.
  • Karama, Sherif ORCID McConnell Brain Imaging Center, Montreal Neurological Institute, Montreal, QC, Canada.
  • Kasperaviciute, Dalia Genomics England, Queen Mary University of London, London, UK.
  • Kaufmann, Tobias ORCID NORMENT - K.G. Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Kelly, Sinead Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA.
  • Kikuchi, Masataka ORCID Department of Genome Informatics, Graduate School of Medicine, Osaka University, Suita, Japan.
  • Klein, Marieke ORCID Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
  • Knapp, Michael Department of Medical Biometry, Informatics and Epidemiology, University Hospital Bonn, Bonn, Germany.
  • Knodt, Annchen R. ORCID Department of Psychology and Neuroscience, Duke University, Durham, NC, USA.
  • Krämer, Bernd ORCID Centre for Translational Research in Systems Neuroscience and Psychiatry, Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany.
  • Lam, Max Human Genetics, Genome Institute of Singapore, Singapore, Singapore.
  • Lancaster, Thomas M. MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.
  • Lee, Phil H. ORCID Department of Psychiatry, Harvard Medical School, Boston, MA, USA.
  • Lett, Tristram A. Division of Mind and Brain Research, Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charité - Universitätsmedizin Berlin corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
  • Lewis, Lindsay B. ORCID McGill Centre for Integrative Neuroscience, McGill University, Montreal, QC, Canada.
  • Lopes-Cendes, Iscia ORCID BRAINN - Brazilian Institute of Neuroscience and Neurotechnology, Campinas, Brazil.
  • Luciano, Michelle ORCID Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.
  • Macciardi, Fabio ORCID Department of Psychiatry and Human Behavior, School of Medicine University of California, Irvine, Irvine, CA, USA.
  • Marquand, Andre F. ORCID Department of Cognitive Neuroscience, Radboud university medical center, Nijmegen, Netherlands.
  • Mathias, Samuel R. Olin Neuropsychiatric Research Center, Institute of Living, Hartford Hospital, Hartford, CT, USA.
  • Melzer, Tracy R. ORCID Brain Research New Zealand - Rangahau Roro Aotearoa, Christchurch, New Zealand.
  • Milaneschi, Yuri Department of Psychiatry, Amsterdam Public Health and Amsterdam Neuroscience, Amsterdam UMC/Vrije Universiteit and GGZ inGeest, Amsterdam, Netherlands.
  • Mirza-Schreiber, Nazanin ORCID Institute of Neurogenomics, Helmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany.
  • Moreira, Jose C. V. ORCID IC - Institute of Computing, Campinas, Brazil.
  • Mühleisen, Thomas W. ORCID Cécile and Oskar Vogt Institute of Brain Research, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
  • Müller-Myhsok, Bertram Institute of Translational Medicine, Liverpool, UK.
  • Najt, Pablo ORCID Centre for Neuroimaging and Cognitive Genomics, National University of Ireland Galway, Galway, Ireland.
  • Nakahara, Soichiro Drug Discovery Research, Astellas Pharmaceuticals, 21 Miyukigaoka, Tsukuba, Ibaraki 305-8585, Japan.
  • Nho, Kwangsik Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Olde Loohuis, Loes M. ORCID Center for Neurobehavioral Genetics, University of California Los Angeles, Los Angeles, CA, USA.
  • Orfanos, Dimitri Papadopoulos ORCID NeuroSpin, CEA, Université Paris-Saclay, Gif-sur-Yvette, France.
  • Pearson, John F. ORCID Department of Pathology and Biomedical Science, University of Otago, Christchurch, Christchurch, New Zealand.
  • Pitcher, Toni L. ORCID Brain Research New Zealand - Rangahau Roro Aotearoa, Christchurch, New Zealand.
  • Pütz, Benno Max Planck Institute of Psychiatry, Munich, Germany.
  • Quidé, Yann ORCID Neuroscience Research Australia, Sydney, NSW, Australia.
  • Ragothaman, Anjanibhargavi ORCID Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA.
  • Rashid, Faisal M. Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA.
  • Reay, William R. ORCID Priority Centre for Brain and Mental Health Research, University of Newcastle, Callaghan, NSW, Australia.
  • Redlich, Ronny Department of Psychiatry, University of Münster, Münster, Germany.
  • Reinbold, Céline S. ORCID Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland.
  • Repple, Jonathan ORCID Department of Psychiatry, University of Münster, Münster, Germany.
  • Richard, Geneviève ORCID Sunnaas Rehabilitation Hospital HT, Nesodden, Norway.
  • Riedel, Brandalyn C. ORCID Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Risacher, Shannon L. Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Rocha, Cristiane S. ORCID BRAINN - Brazilian Institute of Neuroscience and Neurotechnology, Campinas, Brazil.
  • Mota, Nina Roth ORCID Department of Psychiatry, Radboud university medical center, Nijmegen, Netherlands.
  • Salminen, Lauren ORCID Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA.
  • Saremi, Arvin ORCID Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA.
  • Saykin, Andrew J. ORCID Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Schlag, Fenja ORCID Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, Netherlands.
  • Schmaal, Lianne Department of Psychiatry, Vrije Universiteit University Medical Center, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
  • Schofield, Peter R. ORCID School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia.
  • Secolin, Rodrigo ORCID BRAINN - Brazilian Institute of Neuroscience and Neurotechnology, Campinas, Brazil.
  • Shapland, Chin Yang ORCID Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, Netherlands.
  • Shen, Li ORCID Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, PA, USA.
  • Shin, Jean ORCID Population Neuroscience & Developmental Neuroimaging, Bloorview Research Institute, University of Toronto, East York, ON, Canada.
  • Shumskaya, Elena ORCID Donders Centre for Cognitive Neuroimaging, Radboud University, Nijmegen, Netherlands.
  • Sønderby, Ida E. NORMENT - K.G. Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Sprooten, Emma ORCID Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, Netherlands.
  • Tansey, Katherine E. MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.
  • Teumer, Alexander Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.
  • Thalamuthu, Anbupalam ORCID Centre for Healthy Brain Ageing, University of New South Wales, Sydney, NSW, Australia.
  • Tordesillas-Gutiérrez, Diana Centro Investigacion Biomedica en Red Salud Mental, Santander, Spain.
  • Turner, Jessica A. ORCID Mind Research Network, Albuquerque, NM, USA.
  • Uhlmann, Anne Department of Psychiatry, University of Vermont, Burlington, VT, USA.
  • Vallerga, Costanza Ludovica ORCID Institute for Molecular Bioscience, University of Queensland, Brisbane, QLD, Australia.
  • van der Meer, Dennis School of Mental Health and Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands.
  • van Donkelaar, Marjolein M. J. Max Planck Institute for Psycholinguistics, Nijmegen, Netherlands.
  • van Eijk, Liza ORCID Queensland Brain Institute, University of Queensland, St Lucia, QLD, Australia.
  • van Erp, Theo G. M. ORCID Department of Psychiatry and Human Behavior, School of Medicine University of California, Irvine, Irvine, CA, USA.
  • van Haren, Neeltje E. M. ORCID Department of Child and Adolescent Psychiatry/Psychology, Erasmus Medical Center-Sophia Children’s Hospital, Rotterdam, Netherlands.
  • van Rooij, Daan ORCID Department of Cognitive Neuroscience, Radboud university medical center, Nijmegen, Netherlands.
  • van Tol, Marie-José ORCID Cognitive Neuroscience Center, Department of Biomedical Sciences of Cells and Systems, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
  • Veldink, Jan H. ORCID Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
  • Verhoef, Ellen ORCID Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, Netherlands.
  • Walton, Esther ORCID Department of Psychology, University of Bath, Bath, UK.
  • Wang, Mingyuan ORCID Research Division, Institute of Mental Health, Singapore, Singapore.
  • Wang, Yunpeng ORCID NORMENT - K.G. Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Wardlaw, Joanna M. ORCID UK Dementia Research Institute, The University of Edinburgh, Edinburgh, UK.
  • Wen, Wei ORCID Centre for Healthy Brain Ageing, University of New South Wales, Sydney, NSW, Australia.
  • Westlye, Lars T. ORCID Department of Psychology, University of Oslo, Oslo, Norway.
  • Whelan, Christopher D. Department of Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland.
  • Witt, Stephanie H. ORCID Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
  • Wittfeld, Katharina ORCID German Center for Neurodegenerative Diseases Rostock/Greifswald, Greifswald, Germany.
  • Wolf, Christiane ORCID Department of Psychiatry, Psychosomatics and Psychotherapy, University of Würzburg, Würzburg, Germany.
  • Wolfers, Thomas ORCID Department of Human Genetics, Radboud University Medical Center, Nijmegen, Netherlands.
  • Wu, Jing Qin ORCID School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, NSW, Australia.
  • Yasuda, Clarissa L. ORCID Department of Neurology, FCM, UNICAMP, Campinas, Brazil.
  • Zaremba, Dario Department of Psychiatry, University of Münster, Münster, Germany.
  • Zhang, Zuo ORCID Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, UK.
  • Zwiers, Marcel P. Donders Centre for Cognitive Neuroimaging, Radboud University, Nijmegen, Netherlands.
  • Artiges, Eric ORCID INSERM Unit 1000 - Neuroimaging & Psychiatry, Paris Saclay University, Gif sur Yvette, France.
  • Assareh, Amelia A. Centre for Healthy Brain Ageing, University of New South Wales, Sydney, NSW, Australia.
  • Ayesa-Arriola, Rosa ORCID Department of Psychiatry, University Hospital Marqués de Valdecilla, School of Medicine, University of Cantabria–IDIVAL, Santander, Spain.
  • Belger, Aysenil ORCID Department of Psychiatry and Frank Porter Graham Child Development Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Brandt, Christine L. NORMENT - K.G. Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Brown, Gregory G. VA San Diego Healthcare System, San Diego, CA, USA.
  • Cichon, Sven ORCID Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, Jülich, Germany.
  • Curran, Joanne E. ORCID Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA.
  • Davies, Gareth E. Avera Institute for Human Genetics, Sioux Falls, SD, USA.
  • Degenhardt, Franziska Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany.
  • Dennis, Michelle F. ORCID Mental Illness Research Education and Clinical Center for Post Deployment Mental Health, Durham VA Medical Center, Durham, NC, USA.
  • Dietsche, Bruno Department of Psychiatry and Psychotherapy, Philipps-University Marburg, Marburg, Germany.
  • Djurovic, Srdjan ORCID NORMENT, Department of Clinical Science, University of Bergen, Bergen, Norway.
  • Doherty, Colin P. ORCID Future Neuro, Royal College of Surgeons in Ireland, Dublin, Ireland.
  • Espiritu, Ryan Information Sciences Institute, University of Southern California, Los Angeles, CA, USA.
  • Garijo, Daniel ORCID Information Sciences Institute, University of Southern California, Los Angeles, CA, USA.
  • Gil, Yolanda Information Sciences Institute, University of Southern California, Los Angeles, CA, USA.
  • Gowland, Penny A. ORCID Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, UK.
  • Green, Robert C. ORCID Harvard Medical School, Boston, MA, USA.
  • Häusler, Alexander N. ORCID Institute of Experimental Epileptology and Cognition Research, University Hospital Bonn, Germany.
  • Heindel, Walter Department of Clinical Radiology, University of Münster, Münster, Germany.
  • Ho, Beng-Choon ORCID Department of Psychiatry, University of Iowa College of Medicine, Iowa City, IA, USA.
  • Hoffmann, Wolfgang U. ORCID German Center for Neurodegenerative Diseases Rostock/Greifswald, Greifswald, Germany.
  • Holsboer, Florian ORCID HMNC Holding GmbH, Munich, Germany.
  • Homuth, Georg ORCID University Medicine Greifswald, Interfaculty Institute for Genetics and Functional Genomics, Department of Functional Genomics, Greifswald, Germany.
  • Hosten, Norbert ORCID Institute of Diagnostic Radiology and Neuroradiology, Greifswald, Germany.
  • Jack, Clifford R. ORCID Department of Radiology, Mayo Clinic, Rochester, MN, USA.
  • Jang, MiHyun ORCID Information Sciences Institute, University of Southern California, Los Angeles, CA, USA.
  • Jansen, Andreas ORCID Core-Unit Brainimaging, Faculty of Medicine, University of Marburg, Marburg, Germany.
  • Kimbrel, Nathan A. Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA.
  • Kolskår, Knut Sunnaas Rehabilitation Hospital HT, Nesodden, Norway.
  • Koops, Sanne Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
  • Krug, Axel ORCID Department of Psychiatry and Psychotherapy, Philipps-University Marburg, Marburg, Germany.
  • Lim, Kelvin O. ORCID Department of Psychiatry, University of Minnesota, Minneapolis, MN, USA.
  • Luykx, Jurjen J. ORCID GGNet Mental Health, Apeldoorn, Netherlands.
  • Mathalon, Daniel H. ORCID Mental Health Service 116d, Veterans Affairs San Francisco Healthcare System, San Francisco, CA, USA.
  • Mather, Karen A. Centre for Healthy Brain Ageing, University of New South Wales, Sydney, NSW, Australia.
  • Mattay, Venkata S. ORCID Department of Radiology, Johns Hopkins University, Baltimore, MD, USA.
  • Matthews, Sarah MRC Integrative Epidemiology Unit, Department of Population Health Sciences, Bristol Medical School, Bristol, UK.
  • Mayoral Van Son, Jaqueline Department of Psychiatry, University Hospital Marqués de Valdecilla, School of Medicine, University of Cantabria–IDIVAL, Santander, Spain.
  • McEwen, Sarah C. ORCID John Wayne Cancer Institute, Santa Monica, CA, USA.
  • Melle, Ingrid ORCID NORMENT - K.G. Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Morris, Derek W. ORCID Centre for Neuroimaging and Cognitive Genomics, National University of Ireland Galway, Galway, Ireland.
  • Mueller, Bryon A. ORCID Department of Psychiatry, University of Minnesota, Minneapolis, MN, USA.
  • Nauck, Matthias German Centre for Cardiovascular Research, Greifswald, Germany.
  • Nordvik, Jan E. ORCID Sunnaas Rehabilitation Hospital HT, Nesodden, Norway.
  • Nöthen, Markus M. ORCID Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany.
  • O’Leary, Daniel S. ORCID Department of Psychiatry, University of Iowa College of Medicine, Iowa City, IA, USA.
  • Opel, Nils Department of Psychiatry, University of Münster, Münster, Germany.
  • Martinot, Marie-Laure Paillère Child and Adolescent Psychiatry Department, APHP Pitié Salpêtrière Hospital, Paris, France.
  • Pike, G. Bruce Radiology and Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada.
  • Preda, Adrian ORCID School of Medicine, University of California Irvine, Irvine, CA, USA.
  • Quinlan, Erin B. Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, UK.
  • Rasser, Paul E. ORCID Hunter Medical Research Institute, Newcastle, NSW, Australia.
  • Ratnakar, Varun ORCID Information Sciences Institute, University of Southern California, Los Angeles, CA, USA.
  • Reppermund, Simone Department of Developmental Disability Neuropsychiatry, University of New South Wales, Sydney, NSW, Australia.
  • Steen, Vidar M. ORCID Dr. Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway.
  • Tooney, Paul A. Hunter Medical Research Institute, Newcastle, NSW, Australia.
  • Torres, Fábio R. ORCID BRAINN - Brazilian Institute of Neuroscience and Neurotechnology, Campinas, Brazil.
  • Veltman, Dick J. ORCID Department of Psychiatry, Amsterdam Public Health and Amsterdam Neuroscience, Amsterdam UMC/Vrije Universiteit and GGZ inGeest, Amsterdam, Netherlands.
  • Voyvodic, James T. ORCID Duke UNC Brain Imaging and Analysis Center, Duke University Medical Center, Durham, NC, USA.
  • Whelan, Robert ORCID School of Psychology, Trinity College Dublin, Dublin, Ireland.
  • White, Tonya Department of Radiology, Erasmus University Medical Centre, Rotterdam, Netherlands.
  • Yamamori, Hidenaga ORCID Department of Psychiatry, Osaka University Graduate School of Medicine, Suita, Japan.
  • Adams, Hieab H. H. ORCID Department of Clinical Genetics, Erasmus MC Medical Center, Rotterdam, Netherlands.
  • Bis, Joshua C. Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.
  • Debette, Stephanie Department of Neurology, CHU de Bordeaux, Bordeaux, France.
  • Decarli, Charles Department of Neurology, University of California, Davis, Sacramento, CA, USA.
  • Fornage, Myriam Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Gudnason, Vilmundur Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
  • Hofer, Edith Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria.
  • Ikram, M. Arfan Department of Epidemiology, Erasmus MC Medical Center, Rotterdam, Netherlands.
  • Launer, Lenore Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute on Aging, Bethesda, MD, USA.
  • Longstreth, W. T. Departments of Neurology and Epidemiology, University of Washington, Seattle, WA, USA.
  • Lopez, Oscar L. ORCID Medical Informatics, Erasmus MC Medical Center, Rotterdam, Netherlands.
  • Mazoyer, Bernard ORCID Neurodegeneratives Diseases Institute UMR 5293, CNRS, CEA, University of Bordeaux, Bordeaux, France.
  • Mosley, Thomas H. ORCID MIND Center, University of Mississippi Medical Center, Jackson, MS, USA.
  • Roshchupkin, Gennady V. Medical Informatics, Erasmus MC Medical Center, Rotterdam, Netherlands.
  • Satizabal, Claudia L. ORCID Department of Neurology, Boston University School of Medicine, Boston, MA, USA.
  • Schmidt, Reinhold Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, Austria.
  • Seshadri, Sudha ORCID Framingham Heart Study and Department of Neurology, Boston University School of Medicine, Boston, MA, USA.
  • Yang, Qiong Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
  • Alvim, Marina K. M. ORCID Department of Neurology, FCM, UNICAMP, Campinas, Brazil.
  • Ames, David National Ageing Research Institute, Melbourne, VIC, Australia.
  • Anderson, Tim J. ORCID Department of Neurology, Canterbury District Health Board, Christchurch, New Zealand.
  • Andreassen, Ole A. ORCID NORMENT - K.G. Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Arias-Vasquez, Alejandro Department of Psychiatry, Radboud university medical center, Nijmegen, Netherlands.
  • Bastin, Mark E. ORCID Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.
  • Baune, Bernhard T. Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC, Australia.
  • Beckham, Jean C. ORCID VA Mid-Atlantic Mental Illness Research Education and Clinical Center for Post Deployment Mental Health, Durham, VA Healthcare System, Durham, NC, USA.
  • Blangero, John Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA.
  • Boomsma, Dorret I. ORCID Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
  • Brodaty, Henry ORCID Dementia Centre for Research Collaboration, University of New South Wales, Sydney, NSW, Australia.
  • Brunner, Han G. Department of Clinical Genetics and School for Oncology and Developmental Biology (GROW), Maastricht University Medical Center, Maastricht, Netherlands.
  • Buckner, Randy L. Department of Radiology, Massachusetts General Hospital, Boston, MA, USA.
  • Buitelaar, Jan K. ORCID Karakter Child and Adolescent Psychiatry University Center, Nijmegen, Netherlands.
  • Bustillo, Juan R. ORCID Department of Psychiatry, University of New Mexico, Albuquerque, NM, USA.
  • Cahn, Wiepke ORCID Department of Psychiatry, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
  • Cairns, Murray J. ORCID Schizophrenia Research Institute, Randwick, NSW, Australia.
  • Calhoun, Vince ORCID Tri-institutional Center for Translational Research in Neuroimaging and Data Science (TReNDS), Georgia State University, Georgia Institute of Technology, Emory University, Atlanta, GA, USA.
  • Carr, Vaughan J. ORCID Department of Psychiatry, Monash University, Clayton, VIC, Australia.
  • Caseras, Xavier MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.
  • Caspers, Svenja Institute for Anatomy I, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.
  • Cavalleri, Gianpiero L. ORCID The SFI FutureNeuro Research Centre, Dublin, Ireland.
  • Cendes, Fernando Department of Neurology, FCM, UNICAMP, Campinas, Brazil.
  • Corvin, Aiden ORCID Department of Psychiatry, Trinity College Dublin, Dublin, Ireland.
  • Crespo-Facorro, Benedicto ORCID Hospital Universitario Virgen Del Rocio, IBiS, Universidad De Sevilla, Sevilla, Spain.
  • Dalrymple-Alford, John C. ORCID School of Psychology, Speech and Hearing, University of Canterbury, Christchurch, New Zealand.
  • Dannlowski, Udo ORCID Department of Psychiatry, University of Münster, Münster, Germany.
  • de Geus, Eco J. C. ORCID Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
  • Deary, Ian J. Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.
  • Delanty, Norman Future Neuro, Royal College of Surgeons in Ireland, Dublin, Ireland.
  • Depondt, Chantal ORCID Department of Neurology, Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium.
  • Desrivières, Sylvane ORCID Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, UK.
  • Donohoe, Gary ORCID Centre for Neuroimaging and Cognitive Genomics, School of Psychology, National University of Ireland Galway, Galway, Ireland.
  • Espeseth, Thomas ORCID Department of Psychology, University of Oslo, Oslo, Norway.
  • Fernández, Guillén Department of Cognitive Neuroscience, Radboud university medical center, Nijmegen, Netherlands.
  • Fisher, Simon E. ORCID Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, Netherlands.
  • Flor, Herta ORCID Department of Cognitive and Clinical Neuroscience, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
  • Forstner, Andreas J. Centre for Human Genetics, University of Marburg, Marburg, Germany.
  • Francks, Clyde ORCID Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, Netherlands.
  • Franke, Barbara ORCID Department of Psychiatry, Radboud university medical center, Nijmegen, Netherlands.
  • Glahn, David C. Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital and Department of Psychiatry, Harvard Medical School, Boston, MA, USA.
  • Gollub, Randy L. ORCID Department of Radiology, Massachusetts General Hospital, Boston, MA, USA.
  • Grabe, Hans J. German Center for Neurodegenerative Diseases Rostock/Greifswald, Greifswald, Germany.
  • Gruber, Oliver Section for Experimental Psychopathology and Neuroimaging, Department of General Psychiatry, Heidelberg University Hospital, Heidelberg, Germany.
  • Håberg, Asta K. ORCID Department of Radiology and Nuclear Medicine, St. Olavs University Hospital, Trondheim, Norway.
  • Hariri, Ahmad R. Department of Psychology and Neuroscience, Duke University, Durham, NC, USA.
  • Hartman, Catharina A. ORCID University of Groningen, University Medical Center Groningen, Department of Psychiatry, Groningen, Netherlands.
  • Hashimoto, Ryota Department of Pathology of Mental Diseases, National Institute of Mental Health, National Center of Neurology and Psychiatry, Tokyo, Japan.
  • Heinz, Andreas Department of Psychiatry and Psychotherapy, Charité Campus Mitte, Charité - Universitätsmedizin Berlin, Berlin, Germany.
  • Henskens, Frans A. ORCID Health Behaviour Research Group, University of Newcastle, Callaghan, NSW, Australia.
  • Hillegers, Manon H. J. ORCID Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
  • Hoekstra, Pieter J. ORCID Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
  • Holmes, Avram J. ORCID Department of Psychology, Yale University, New Haven, CT, USA.
  • Hong, L. Elliot Maryland Psychiatry Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.
  • Hopkins, William D. Department of Comparative Medicine, The University of Texas MD Anderson Cancer Center, Bastrop, TX, USA.
  • Hulshoff Pol, Hilleke E. ORCID Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
  • Jernigan, Terry L. Center for Human Development, University of California San Diego, La Jolla, CA, USA.
  • Jönsson, Erik G. ORCID Centre for Psychiatric Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
  • Kahn, René S. Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Kennedy, Martin A. ORCID Department of Pathology and Biomedical Science, University of Otago, Christchurch, Christchurch, New Zealand.
  • Kircher, Tilo T. J. ORCID Department of Psychiatry and Psychotherapy, Philipps-University Marburg, Marburg, Germany.
  • Kochunov, Peter Maryland Psychiatry Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.
  • Kwok, John B. J. ORCID Neurogenetics and Epigenetics, Brain and Mind Centre, The University of Sydney, Sydney, NSW, Australia.
  • Le Hellard, Stephanie ORCID Dr. Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway.
  • Loughland, Carmel M. Hunter New England Mental Health Service, Newcastle, NSW, Australia.
  • Martin, Nicholas G. ORCID Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
  • Martinot, Jean-Luc INSERM Unit 1000 - Neuroimaging & Psychiatry, Paris Saclay University, Gif sur Yvette, France.
  • McDonald, Colm Centre for Neuroimaging and Cognitive Genomics, National University of Ireland Galway, Galway, Ireland.
  • McMahon, Katie L. ORCID Herston Imaging Research Facility, School of Clinical Sciences, Queensland University of Technology, Brisbane, QLD, Australia.
  • Meyer-Lindenberg, Andreas ORCID Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
  • Michie, Patricia T. ORCID School of Psychology, University of Newcastle, Callaghan, NSW, Australia.
  • Morey, Rajendra A. ORCID Mental Illness Research Education and Clinical Center for Post Deployment Mental Health, Durham VA Medical Center, Durham, NC, USA.
  • Mowry, Bryan ORCID Queensland Centre for Mental Health Research, University of Queensland, Brisbane, QLD, Australia.
  • Nyberg, Lars Department of Radiation Sciences, Umeå University, Umeå, Sweden.
  • Oosterlaan, Jaap ORCID Clinical Neuropsychology section, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
  • Ophoff, Roel A. ORCID Center for Neurobehavioral Genetics, University of California Los Angeles, Los Angeles, CA, USA.
  • Pantelis, Christos ORCID NorthWestern Mental Health, Sunshine Hospital, St Albans, VIC, Australia.
  • Paus, Tomas Centre for Developing Brain, Child Mind Institute, New York, NY, USA.
  • Pausova, Zdenka ORCID Department of Physiology, University of Toronto, Toronto, ON, Canada.
  • Penninx, Brenda W. J. H. ORCID Department of Psychiatry, Amsterdam Public Health and Amsterdam Neuroscience, Amsterdam UMC/Vrije Universiteit and GGZ inGeest, Amsterdam, Netherlands.
  • Polderman, Tinca J. C. ORCID Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
  • Posthuma, Danielle ORCID Department of Clinical Genetics, Vrije Universiteit Medical Centre, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
  • Rietschel, Marcella ORCID Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
  • Roffman, Joshua L. ORCID Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
  • Rowland, Laura M. Maryland Psychiatry Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.
  • Sachdev, Perminder S. ORCID Neuropsychiatric Institute, The Prince of Wales Hospital, Sydney, NSW, Australia.
  • Sämann, Philipp G. Max Planck Institute of Psychiatry, Munich, Germany.
  • Schall, Ulrich ORCID Hunter Medical Research Institute, Newcastle, NSW, Australia.
  • Schumann, Gunter Leibniz Institute for Neurobiology, Magdeburg, Germany.
  • Scott, Rodney J. ORCID Division of Molecular Medicine, John Hunter Hospital, New Lambton Heights, NSW, Australia.
  • Sim, Kang ORCID General Psychiatry, Institute of Mental Health, Singapore, Singapore.
  • Sisodiya, Sanjay M. Chalfont Centre for Epilepsy, Chalfont-St-Peter, UK.
  • Smoller, Jordan W. Stanley Center for Psychiatric Research, Broad Institute, Boston, MA, USA.
  • Sommer, Iris E. ORCID Department of Medical and Biological Psychology, University of Bergen, Bergen, Norway.
  • St Pourcain, Beate ORCID MRC Integrative Epidemiology Unit, Department of Population Health Sciences, Bristol Medical School, Bristol, UK.
  • Stein, Dan J. ORCID MRC Unit on Risk & Resilience in Mental Disorders, University of Cape Town, Cape Town, South Africa.
  • Toga, Arthur W. ORCID Laboratory of Neuro Imaging, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
  • Trollor, Julian N. ORCID Department of Developmental Disability Neuropsychiatry, University of New South Wales, Sydney, NSW, Australia.
  • Van der Wee, Nic J. A. ORCID Department of Psychiatry, Leiden University Medical Center, Leiden, Netherlands.
  • van ’t Ent, Dennis ORCID Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
  • Völzke, Henry Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.
  • Walter, Henrik ORCID Division of Mind and Brain Research, Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charité - Universitätsmedizin Berlin corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
  • Weber, Bernd ORCID Institute of Experimental Epileptology and Cognition Research, University Hospital Bonn, Germany.
  • Weinberger, Daniel R. ORCID Psychiatry, Neurology, Neuroscience, Genetics, Johns Hopkins University, Baltimore, MD, USA.
  • Wright, Margaret J. ORCID Centre for Advanced Imaging, University of Queensland, Brisbane, QLD, Australia.
  • Zhou, Juan ORCID Center for Cognitive Neuroscience, Neuroscience and Behavioral Disorders Program, Duke–National University of Singapore Medical School, Singapore, Singapore.
  • Stein, Jason L. ORCID Department of Genetics and UNC Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Thompson, Paul M. ORCID Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA.
  • Medland, Sarah E. ORCID Faculty of Medicine, University of Queensland, Brisbane, QLD, Australia.
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  • 2020-3-19
Published in:
  • Science. - American Association for the Advancement of Science (AAAS). - 2020, vol. 367, no. 6484, p. eaay6690
English The cerebral cortex underlies our complex cognitive capabilities, yet little is known about the specific genetic loci that influence human cortical structure. To identify genetic variants that affect cortical structure, we conducted a genome-wide association meta-analysis of brain magnetic resonance imaging data from 51,665 individuals. We analyzed the surface area and average thickness of the whole cortex and 34 regions with known functional specializations. We identified 199 significant loci and found significant enrichment for loci influencing total surface area within regulatory elements that are active during prenatal cortical development, supporting the radial unit hypothesis. Loci that affect regional surface area cluster near genes in Wnt signaling pathways, which influence progenitor expansion and areal identity. Variation in cortical structure is genetically correlated with cognitive function, Parkinson’s disease, insomnia, depression, neuroticism, and attention deficit hyperactivity disorder.
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