Journal article
Non-sustained ventricular tachycardia in patients with congenital heart disease: An important sign?
- Teuwen CP Dept of Cardiology, Erasmus University Medical Center, Rotterdam, The Netherlands.
- Ramdjan TT Dept of Cardiology, Erasmus University Medical Center, Rotterdam, The Netherlands.
- Götte M Dept of Cardiology, Haga Hospital, The Hague, The Netherlands.
- Brundel BJ Dept of Clinical Pharmacy and Pharmacology, University Medical Center, University of Groningen, The Netherlands.
- Evertz R Dept of Cardiology, Radboud University Medical Center, Nijmegen, The Netherlands.
- Vriend JW Dept of Cardiology, Haga Hospital, The Hague, The Netherlands.
- Molhoek SG Dept of Cardiology, Amphia Hospital, Breda, The Netherlands.
- Reinhart Dorman HG Dept of Cardiology, Medisch Spectrum Twente, Enschede, The Netherlands.
- van Opstal JM Dept of Cardiology, Medisch Spectrum Twente, Enschede, The Netherlands.
- Konings TC Dept of Cardiology, VU University Medical Center, Amsterdam, The Netherlands.
- van der Voort P Dept of Cardiology, Catharina Hospital, Eindhoven, The Netherlands.
- Delacretaz E Dept of Cardiology, Inselspital, University of Bern, Switzerland.
- Wolfhagen NJ Dept of Cardiology, Erasmus University Medical Center, Rotterdam, The Netherlands.
- van Gastel V Dept of Cardiology, Erasmus University Medical Center, Rotterdam, The Netherlands.
- de Klerk P Dept of Cardiology, Erasmus University Medical Center, Rotterdam, The Netherlands.
- Theuns DA Dept of Cardiology, Erasmus University Medical Center, Rotterdam, The Netherlands.
- Witsenburg M Dept of Cardiology, Erasmus University Medical Center, Rotterdam, The Netherlands.
- Roos-Hesselink JW Dept of Cardiology, Erasmus University Medical Center, Rotterdam, The Netherlands.
- Triedman JK Dept of Cardiology, Boston Children's Hospital, Boston, USA.
- Bogers AJ Dept of Cardio-Thoracic Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands.
- de Groot NM Dept of Cardiology, Erasmus University Medical Center, Rotterdam, The Netherlands. Electronic address: n.m.s.degroot@erasmusmc.nl.
- 2016-01-26
Published in:
- International journal of cardiology. - 2016
Congenital heart defects
Implantable cardioverter defibrillator
Ventricular tachyarrhythmia
Adult
Age of Onset
Defibrillators, Implantable
Female
Heart Defects, Congenital
Humans
Male
Middle Aged
Retrospective Studies
Tachycardia, Ventricular
Treatment Outcome
English
BACKGROUND
Sustained ventricular tachycardia (susVT) and ventricular fibrillation (VF) are observed in adult patients with congenital heart disease (CHD). These dysrhythmias may be preceded by non-sustained ventricular tachycardia (NSVT). The aims of this study are to examine the 1] time course of ventricular tachyarrhythmia (VTA) in a large cohort of patients with various CHDs and 2] the development of susVT/VF after NSVT.
METHODS
In this retrospective study, patients with VTA on ECG, 24-hour Holter or ICD-printout or an out-of-hospital-cardiac arrest due to VF were included. In patients with an ICD, the number of shocks was studied.
RESULTS
Patients (N=145 patients, 59% male) initially presented with NSVT (N=103), susVT (N=25) or VF (N=17) at a mean age of 40 ± 14 years. Prior to VTA, 58 patients had intraventricular conduction delay, 14 an impaired ventricular dysfunction and 3 had coronary artery disease. susVT/VF rarely occurred in patients with NSVT (N=5). Fifty-two (36%) patients received an ICD; appropriate and inappropriate shocks, mainly due to supraventricular tachycardia (SVT), occurred in respectively 15 (29%) (NSVT: N=1, susVT: N=9, VF: N=5) and 12 (23%) (NSVT: N=4, susVT: N=5, VF: N=3) patients.
CONCLUSIONS
VTA in patients with CHD appear on average at the age of 40 years. susVT/VF rarely developed in patients with only NSVT, whereas recurrent episodes of susVT/VF frequently developed in patients initially presenting with susVT/VF. Hence, a wait-and-see treatment strategy in patients with NSVT and aggressive therapy of both episodes of VTA and SVT in patients with susVT/VF seems justified.
Sustained ventricular tachycardia (susVT) and ventricular fibrillation (VF) are observed in adult patients with congenital heart disease (CHD). These dysrhythmias may be preceded by non-sustained ventricular tachycardia (NSVT). The aims of this study are to examine the 1] time course of ventricular tachyarrhythmia (VTA) in a large cohort of patients with various CHDs and 2] the development of susVT/VF after NSVT.
METHODS
In this retrospective study, patients with VTA on ECG, 24-hour Holter or ICD-printout or an out-of-hospital-cardiac arrest due to VF were included. In patients with an ICD, the number of shocks was studied.
RESULTS
Patients (N=145 patients, 59% male) initially presented with NSVT (N=103), susVT (N=25) or VF (N=17) at a mean age of 40 ± 14 years. Prior to VTA, 58 patients had intraventricular conduction delay, 14 an impaired ventricular dysfunction and 3 had coronary artery disease. susVT/VF rarely occurred in patients with NSVT (N=5). Fifty-two (36%) patients received an ICD; appropriate and inappropriate shocks, mainly due to supraventricular tachycardia (SVT), occurred in respectively 15 (29%) (NSVT: N=1, susVT: N=9, VF: N=5) and 12 (23%) (NSVT: N=4, susVT: N=5, VF: N=3) patients.
CONCLUSIONS
VTA in patients with CHD appear on average at the age of 40 years. susVT/VF rarely developed in patients with only NSVT, whereas recurrent episodes of susVT/VF frequently developed in patients initially presenting with susVT/VF. Hence, a wait-and-see treatment strategy in patients with NSVT and aggressive therapy of both episodes of VTA and SVT in patients with susVT/VF seems justified.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1016/j.ijcard.2016.01.042
- PMID 26805391
- Persistent URL
- https://sonar.ch/global/documents/58266
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