Elaboration of D-(-)-ribose into a tricyclic, natural product-like scaffold.
Journal article

Elaboration of D-(-)-ribose into a tricyclic, natural product-like scaffold.

  • 2004-11-20
Published in:
  • The Journal of organic chemistry. - 2004
English The construction of natural product-like, tricyclic compounds is reported. Starting from a D-(-)-ribose-derived dihydrofurane, the tricyclic scaffold is prepared via an intramolecular hetero-Diels-Alder reaction. The reaction proceeds with very high diastereoselectivity through an endo transition state, as established on the basis of X-ray structural analysis of the products. Further modification and derivatization of the obtained products is described.
Language
  • English
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closed
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Persistent URL
https://sonar.ch/global/documents/58898
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