Staphylococcal Enterotoxin C-An Update on SEC Variants, Their Structure and Properties, and Their Role in Foodborne Intoxications.
- Etter D Institute for Food Safety and Hygiene, Vetsuisse Faculty, University of Zürich, 8057 Zürich, Switzerland.
- Schelin J Division of Applied Microbiology, Department of Chemistry, Lund University, 22100 Lund, Sweden.
- Schuppler M Laboratory of Food Microbiology, Institute of Food, Nutrition and Health, ETH Zürich, 8092 Zürich, Switzerland.
- Johler S Institute for Food Safety and Hygiene, Vetsuisse Faculty, University of Zürich, 8057 Zürich, Switzerland.
- 2020-09-15
Published in:
- Toxins. - 2020
English
Staphylococcal enterotoxins are the most common cause of foodborne intoxications (staphylococcal food poisoning) and cause a wide range of diseases. With at least six variants staphylococcal enterotoxin C (SEC) stands out as particularly diverse amongst the 25 known staphylococcal enterotoxins. Some variants present unique and even host-specific features. Here, we review the role of SEC in human and animal health with a particular focus on its role as a causative agent for foodborne intoxications. We highlight structural features unique to SEC and its variants, particularly, the emetic and superantigen activity, as well as the roles of SEC in mastitis and in dairy products. Information about the genetic organization as well as regulatory mechanisms including the accessory gene regulator and food-related stressors are provided.
- Language
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- English
- Open access status
- gold
- Identifiers
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- DOI 10.3390/toxins12090584
- PMID 32927913
- Persistent URL
- https://sonar.ch/global/documents/61575
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