Establishment of a human skeletal muscle-derived cell line: biochemical, cellular and electrophysiological characterization
- Rokach, Ori Department of Biomedicine, University Hospital Basel, Hebelstrasse 20, 4031 Basel, Switzerland
- Ullrich, Nina D. Department of Physiology, University of Bern, Bern, Switzerland
- Rausch, Martin Novartis Biomedical Institute, Postfach 4002 Basel, Switzerland
- Mouly, Vincent Thérapie des maladies du muscle strié, Institut de Myologie, UM76, UPMC, Université Paris 6, Paris, France
- Zhou, Haiyan Dubowitz Neuromuscular Centre, Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, U.K.
- Muntoni, Francesco Dubowitz Neuromuscular Centre, Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, U.K.
- Zorzato, Francesco Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy
- Treves, Susan Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy
- 2013-9-27
Published in:
- Biochemical Journal. - Portland Press Ltd.. - 2013, vol. 455, no. 2, p. 169-177
English
We characterized excitation–contraction coupling of an immortalized human skeletal muscle cell line and show the potential application of this cell line as a platform for the screaning of drugs to treating defects caused by mutations in genes involved in Ca2+ regulation.
- Language
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- English
- Open access status
- green
- Identifiers
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- DOI 10.1042/bj20130698
- ISSN 0264-6021
- Persistent URL
- https://sonar.ch/global/documents/6447
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