Stereodivergence in Asymmetric Catalysis.

Krautwald S; Carreira EM

doi:10.1021/jacs.6b13340

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Journal article

Stereodivergence in Asymmetric Catalysis.

Krautwald S Eidgenössische Technische Hochschule Zürich , 8093 Zürich, Switzerland.
Carreira EM Eidgenössische Technische Hochschule Zürich , 8093 Zürich, Switzerland.

2017-04-07

Published in:

Journal of the American Chemical Society. - 2017

English This Perspective presents an overview of catalytic enantioselective transformations that allow convenient access to all stereoisomers of a given product with multiple stereogenic centers. Particular focus is placed on discussion of the concept of stereodivergent dual catalysis and its application in target-oriented synthesis. The potential of this concept in the development of new transformations as well as implications for achieving stereochemical diversity in library design and diversity-oriented synthesis are also discussed.

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