The endoplasmic reticulum: a sensor of cellular stress that modulates immune responses.
- Martinon F Dept. of Biochemistry, University of Lausanne, 155 Ch. Des Boveresses, Epalinges 1066, Switzerland. fabio.martinon@unil.ch
- 2012-07-18
Published in:
- Microbes and infection. - 2012
Animals
Endoplasmic Reticulum
Endoplasmic Reticulum Stress
Humans
Immunity, Innate
Signal Transduction
Stress, Physiological
English
Many inflammatory and infectious diseases are characterized by the activation of signaling pathways steaming from the endoplasmic reticulum (ER). These pathways, primarily associated with loss of ER homeostasis, are emerging as key regulators of inflammation and infection. Recent advances shed light on the mechanisms linking ER-stress and immune responses.
- Language
-
- English
- Open access status
- green
- Identifiers
-
- DOI 10.1016/j.micinf.2012.07.005
- PMID 22800981
- Persistent URL
- https://sonar.ch/global/documents/658
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