Journal article
Snake venom C-type lectins as tools in platelet research.
- Clemetson KJ Theodor Kocher Institute, University of Berne, Switzerland. clemetson@tki.unibe.ch
- Polgár J
- Clemetson JM
- 2006-06-24
Published in:
- Platelets. - 1998
English
The snake C-type lectins are a major group of proteins present in venoms that fold to a structure with similarities to classic C-type lectins. The loop that would be involved in calcium and sugar binding is truncated and heterodimers are linked by a disulphide bond and by swapping loop domains between the subunits. M any of these C-type lectins interact with platelet receptors to inhibit or induce platelet activation. The use of these C-type lectins to investigate platelet function is discussed and illustrated with specific examples.
- Language
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- English
- Open access status
- closed
- Identifiers
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- DOI 10.1080/09537109876636
- PMID 16793696
- Persistent URL
- https://sonar.ch/global/documents/6690
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