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Cell culture-based biosensing techniques for detecting toxicity in water.
Journal article

Cell culture-based biosensing techniques for detecting toxicity in water.

  • Tan L Department of Environmental Toxicology, Eawag, Swiss Federal Institute of Aquatic Science and Technology, Überlandstrasse 133, 8600 Dübendorf, Switzerland.
  • Schirmer K Department of Environmental Toxicology, Eawag, Swiss Federal Institute of Aquatic Science and Technology, Überlandstrasse 133, 8600 Dübendorf, Switzerland; School of Architecture, Civil and Environmental Engineering (ENAC), EPF Lausanne, 1015 Lausanne, Switzerland; Institute of Biogeochemistry and Pollutant Dynamics, ETH Zürich, 8092 Zürich, Switzerland. Electronic address: kristin.schirmer@eawag.ch.
  • 2017-01-31
Published in:
  • Current opinion in biotechnology. - 2017
Animals
Biosensing Techniques
Cell Culture Techniques
Fishes
Fresh Water
Humans
Toxicity Tests
Water
Water Pollutants, Chemical
Water Quality
English The significant increase of contaminants entering fresh water bodies calls for the development of rapid and reliable methods to monitor the aquatic environment and to detect water toxicity. Cell culture-based biosensing techniques utilise the overall cytotoxic response to external stimuli, mediated by a transduced signal, to specify the toxicity of aqueous samples. These biosensing techniques can effectively indicate water toxicity for human safety and aquatic organism health. In this review we account for the recent developments of the mainstream cell culture-based biosensing techniques for water quality evaluation, discuss their key features, potentials and limitations, and outline the future prospects of their development.
Language
  • English
Open access status
hybrid
Identifiers
Persistent URL
https://sonar.ch/global/documents/68296
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