Refining the definition of hypereosinophilic syndrome.
- Simon HU Institute of Pharmacology, University of Bern, Switzerland. hus@pki.unibe.ch
- Rothenberg ME
- Bochner BS
- Weller PF
- Wardlaw AJ
- Wechsler ME
- Rosenwasser LJ
- Roufosse F
- Gleich GJ
- Klion AD
- 2010-07-20
Published in:
- The Journal of allergy and clinical immunology. - 2010
English
Because of advances in our understanding of the hypereosinophilic syndrome (HES) and the availability of novel therapeutic agents, the original criteria defining these disorders are becoming increasingly problematic. Here, we discuss shortcomings with the current definition of HES and recent developments in the classification of these disorders. Despite significant progress in our understanding of the pathogenesis of some forms of HES, the current state of knowledge is still insufficient to formulate a new comprehensive etiologic definition of HESs. Nevertheless, we suggest a new working definition that overcomes some of the most obvious limitations with the original definition.
- Language
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- English
- Open access status
- green
- Identifiers
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- DOI 10.1016/j.jaci.2010.03.042
- PMID 20639008
- Persistent URL
- https://sonar.ch/global/documents/6873
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