Cytokines of the IL-17 family in psoriasis.
- Lauffer F Department of Dermatology and Allergy Biederstein, University hospital of the Technical University Munich (TUM), Munich, Germany.
- Eyerich K Department of Dermatology and Allergy Biederstein, University hospital of the Technical University Munich (TUM), Munich, Germany.
- Boehncke WH Division of Dermatology and Venereology and Department of Pathology and Immunology, University Hospital of Geneva, University of Geneva, Geneva, Switzerland.
- Asadullah K Dermatology practice Potsdam, Potsdam, Germany.
- Beissert S Department of Dermatology, Carl Gustav Carus University Medical Center, Dresden Technical University, Dresden, Germany.
- Ghoreschi K Department of Dermatology, Venereology and Allergology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
- Schön MP Department of Dermatology, Venereology and Allergology, University Medical Center, Göttingen University, Göttingen, Germany.
- 2020-05-25
Published in:
- Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG. - 2020
English
Various immune cells and their messenger substances influence the development of psoriasis. Cytokines of the IL-17 family are of particular importance. In addition to IL-17A, which plays a central role in the pathogenesis of psoriasis, other subtypes of the IL-17 family also have a proinflammatory effect. This review provides an up-to-date overview of the immunopathogenesis of psoriasis with regard to the six IL-17 subtypes, in particular their physiological and pathogenic properties, as well as their significance for psoriasis therapy.
- Language
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- English
- Open access status
- hybrid
- Identifiers
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- DOI 10.1111/ddg.14124
- PMID 32447845
- Persistent URL
- https://sonar.ch/global/documents/70136
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