Professional differences in antigen presentation to iNKT cells.
De Libero GExperimental Immunology, Department of Biomedicine, University Hospital Basel, Basel, Switzerland and Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A(∗)STAR), Biopolis, Singapore. Electronic address: gennaro_delibero@immunol.a-star.edu.sg.
Mori LExperimental Immunology, Department of Biomedicine, University Hospital Basel, Basel, Switzerland and Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A(∗)STAR), Biopolis, Singapore.
English
Invariant natural killer T cells are preactivated lymphocytes that react upon recognition of CD1d-antigen complexes. Accordingly, any type of CD1d-positive cell could behave as antigen-presenting cell (APC). In this issue of Immunity, Arora et al. (2014), report that professional APCs still make the difference.