Acquisition of Bioelectrical Signals with Small Electrodes.
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Viswam V
ETH Zurich, Department of Biosystems Science and Engineering, Basel, Switzerland.
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Obien M
ETH Zurich, Department of Biosystems Science and Engineering, Basel, Switzerland.
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Frey U
ETH Zurich, Department of Biosystems Science and Engineering, Basel, Switzerland.
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Franke F
ETH Zurich, Department of Biosystems Science and Engineering, Basel, Switzerland.
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Hierlemann A
ETH Zurich, Department of Biosystems Science and Engineering, Basel, Switzerland.
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Published in:
- IEEE Biomedical Circuits and Systems Conference : healthcare technology : [proceedings]. IEEE Biomedical Circuits and Systems Conference. - 2018
English
Although the mechanisms of recording bioelectrical signals from different types of electrogenic cells (neurons, cardiac cells etc.) by means of planar metal electrodes have been extensively studied, the recording characteristics and conditions for very small electrode sizes are not yet established. Here, we present a combined experimental and computational approach to elucidate, how the electrode size influences the recorded signals, and how inherent properties of the electrode, such as impedance, noise, and transmission characteristics shape the signal. We demonstrate that good quality recordings can be achieved with electrode diameters of less than 10 µm, provided that impedance reduction measures have been implemented and provided that a set of requirements for signal amplification has been met.
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Language
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Open access status
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green
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Persistent URL
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https://sonar.ch/global/documents/78702
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