Journal article
Visual complaints and visual hallucinations in Parkinson's disease.
- Urwyler P Gerontechnology & Rehabilitation Group, University of Bern, Bern, Switzerland.
- Nef T Gerontechnology & Rehabilitation Group, University of Bern, Bern, Switzerland; ARTORG Center for Biomedical Engineering Research, University of Bern, Bern, Switzerland.
- Killen A Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, United Kingdom.
- Collerton D Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, United Kingdom; Northumberland, Tyne & Wear NHS Foundation Trust, Bensham Hospital, Gateshead, United Kingdom.
- Thomas A Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, United Kingdom; Northumberland, Tyne & Wear NHS Foundation Trust, Bensham Hospital, Gateshead, United Kingdom.
- Burn D Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, United Kingdom.
- McKeith I Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, United Kingdom.
- Mosimann UP Gerontechnology & Rehabilitation Group, University of Bern, Bern, Switzerland; Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Old Age Psychiatry, University Hospital of Psychiatry, University of Bern, Switzerland. Electronic address: urs.mosimann@gef.be.ch.
- 2014-01-11
Published in:
- Parkinsonism & related disorders. - 2014
Parkinson's disease
Visual complaints
Visual hallucinations
Aged
Aged, 80 and over
Cross-Sectional Studies
Diplopia
Female
Hallucinations
Humans
Male
Middle Aged
Parkinson Disease
Vision Disorders
English
BACKGROUND
Visual symptoms are common in Parkinson's disease (PD) and are frequently under-diagnosed. The detection of visual symptoms is important for differential diagnosis and patient management.
AIM
To establish the prevalence of recurrent visual complaints (RVC) and recurrent visual hallucinations (RVH) and to investigate their interaction in PD patients and controls.
METHODS
This cross-sectional study included 88 PD patients and 90 controls. RVC and RVH were assessed with a visual symptom questionnaire and the North-East-Visual-Hallucinations-Interview (NEVHI).
RESULTS
Double vision (PD vs.
CONTROLS
18.2% vs. 1.3%; p < 0.001), misjudging objects when walking (PD vs.
CONTROLS
12.5% vs. 1.3%; p < 0.01), words moving whilst reading (PD vs.
CONTROLS
17.0% vs. 1.3%; p < 0.001) and freezing in narrow spaces (PD vs.
CONTROLS
30.7% vs. 0%; p < 0.001) were almost exclusively found in PD patients. The same was true for recurrent complex visual hallucinations and illusions (PD vs.
CONTROLS
both 17.0% vs. 0%; p < 0.001). Multiple RVC (43.2% vs. 15.8%) and multiple RVH (29.5% vs. 5.6%) were also more common in PD patients (both p < 0.001). RVC did not predict recurrent complex visual hallucinations; but double vision (p = 0.018, R(2) = 0.302) and misjudging objects (p = 0.002, R(2) = 0.302) predicted passage hallucinations. Misjudging objects also predicted the feeling of presence (p = 0.010, R(2) = 0.321).
CONCLUSIONS
Multiple and recurrent visual symptoms are common in PD. RVC emerged as risk factors predictive of the minor forms of hallucinations, but not recurrent complex visual hallucinations.
Visual symptoms are common in Parkinson's disease (PD) and are frequently under-diagnosed. The detection of visual symptoms is important for differential diagnosis and patient management.
AIM
To establish the prevalence of recurrent visual complaints (RVC) and recurrent visual hallucinations (RVH) and to investigate their interaction in PD patients and controls.
METHODS
This cross-sectional study included 88 PD patients and 90 controls. RVC and RVH were assessed with a visual symptom questionnaire and the North-East-Visual-Hallucinations-Interview (NEVHI).
RESULTS
Double vision (PD vs.
CONTROLS
18.2% vs. 1.3%; p < 0.001), misjudging objects when walking (PD vs.
CONTROLS
12.5% vs. 1.3%; p < 0.01), words moving whilst reading (PD vs.
CONTROLS
17.0% vs. 1.3%; p < 0.001) and freezing in narrow spaces (PD vs.
CONTROLS
30.7% vs. 0%; p < 0.001) were almost exclusively found in PD patients. The same was true for recurrent complex visual hallucinations and illusions (PD vs.
CONTROLS
both 17.0% vs. 0%; p < 0.001). Multiple RVC (43.2% vs. 15.8%) and multiple RVH (29.5% vs. 5.6%) were also more common in PD patients (both p < 0.001). RVC did not predict recurrent complex visual hallucinations; but double vision (p = 0.018, R(2) = 0.302) and misjudging objects (p = 0.002, R(2) = 0.302) predicted passage hallucinations. Misjudging objects also predicted the feeling of presence (p = 0.010, R(2) = 0.321).
CONCLUSIONS
Multiple and recurrent visual symptoms are common in PD. RVC emerged as risk factors predictive of the minor forms of hallucinations, but not recurrent complex visual hallucinations.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1016/j.parkreldis.2013.12.009
- PMID 24405755
- Persistent URL
- https://sonar.ch/global/documents/79823
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