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Journal article

Nogo-A represses anatomical and synaptic plasticity in the central nervous system.

  • Kempf A Brain Research Institute, University of Zurich, Switzerland. kempf@hifo.uzh.ch
  • Schwab ME
  • 2013-05-03
Published in:
  • Physiology (Bethesda, Md.). - 2013
Animals
Central Nervous System
Humans
Myelin Proteins
Myelin Sheath
Nerve Regeneration
Neuronal Plasticity
Neurons
Nogo Proteins
Receptors, Cell Surface
Synaptic Transmission
Trauma, Nervous System
English Nogo-A was initially discovered as a myelin-associated growth inhibitory protein limiting axonal regeneration after central nervous system (CNS) injury. This review summarizes current knowledge on how myelin and neuronal Nogo-A and its receptors exert physiological functions ranging from the regulation of growth suppression to synaptic plasticity in the developing and adult intact CNS.
Language
  • English
Open access status
green
Identifiers
Persistent URL
https://sonar.ch/global/documents/82232
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