Morphological and functional assessment of the uterus: "one-stop shop imaging" using a compressed-sensing accelerated, free-breathing T1-VIBE sequence.
Journal article

Morphological and functional assessment of the uterus: "one-stop shop imaging" using a compressed-sensing accelerated, free-breathing T1-VIBE sequence.

  • Hausmann D Department of Radiology, Kantonsspital Baden, Baden, Switzerland.
  • Kreul D Siemens Healthcare AG, Zürich, Switzerland.
  • Klarhöfer M Siemens Healthcare AG, Zürich, Switzerland.
  • Nickel D MR Applications Predevelopment, Siemens Healthcare GmbH, Erlangen, Germany.
  • Grimm R MR Applications Predevelopment, Siemens Healthcare GmbH, Erlangen, Germany.
  • Kiefer B MR Applications Predevelopment, Siemens Healthcare GmbH, Erlangen, Germany.
  • Riffel P Department of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
  • Attenberger UI Department of Radiology, University Hospital Bonn, Bonn, Germany.
  • Zöllner FG Computer Assisted Clinical Medicine, Mannheim Institute for Intelligent Systems in Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
  • Kubik-Huch RA Department of Radiology, Kantonsspital Baden, Baden, Switzerland.
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  • 2020-07-01
Published in:
  • Acta radiologica (Stockholm, Sweden : 1987). - 2020
English BACKGROUND
The combination of motion-insensitive, high-temporal, and spatial resolution imaging with evaluation of quantitative perfusion has the potential to increase the diagnostic capabilities of magnetic resonance imaging (MRI) in the female pelvis.


PURPOSE
To compare a free-breathing compressed-sensing VIBE (fbVIBE) with flexible temporal resolution (range = 4.6-13.8 s) with breath-hold VIBE (bhVIBE) and to evaluate the potential value of quantifying uterine perfusion.


MATERIAL AND METHODS
A total of 70 datasets from 60 patients (bhVIBE: n = 30; fbVIBE: n = 40) were evaluated by two radiologists. Only temporally resolved reconstruction (fbVIBE) was performed on 30 of the fbVIBE datasets. For a subset (n = 10) of the fbVIBE acquisitions, a time- and motion-resolved reconstruction (mrVIBE) was evaluated. Image quality (IQ), artifacts, diagnostic confidence (DC), and delineation of uterine structures (DoS) were graded on Likert scales (IQ/DC/DoS: 1 (non-diagnostic) to 5 (perfect); artifacts: 1 (no artifacts) to 5 (severe artifacts)). A Tofts model was applied for perfusion analysis. Ktrans was obtained in the myometrium (Mm), junctional zone (Jz), and cervix (Cx).


RESULTS
The median IQ/DoS/DC scores of fbVIBE (4/5/5 κ >0.7-0.9) and bhVIBE (4/4/4; κ = 0.5-0.7; P > 0.05) were high, but Artifacts were graded low (fbVIBE/bhVIBE: 2/2; κ = 0.6/0.5; P > 0.05). Artifacts were only slightly improved by the additional motion-resolved reconstruction (fbVIBE/mrVIBE: 2/1.5; P = 0.08); fbVIBE was preferred in most cases (7/10). Significant differences of Ktrans values were found between Cx, Jz, and Mm (0.12/0.21/0.19; P < 0.05).


CONCLUSION
The fbVIBE sequence allows functional and morphological assessment of the uterus at comparable IQ to bhVIBE.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://sonar.ch/global/documents/8266
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