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Biological functions of lymphatic vessels.
Journal article

Biological functions of lymphatic vessels.

  • Petrova TV Department of Oncology and Ludwig Institute for Cancer Research, University of Lausanne and Centre Hospitalier Universitaire Vaudois, Chemin des Boveresses 155 CH-1066 Epalinges, Switzerland. tatiana.petrova@unil.ch gykoh@kaist.ac.kr.
  • Koh GY Center for Vascular Research, Institute for Basic Science, Daejeon, 34141, Republic of Korea. tatiana.petrova@unil.ch gykoh@kaist.ac.kr.
  • 2020-07-11
Published in:
  • Science (New York, N.Y.). - 2020
Animals
Central Nervous System
Central Nervous System Infections
Cerebrospinal Fluid
Encephalitis
Homeostasis
Humans
Immunologic Surveillance
Intestines
Lymphatic Vessels
Mice
Neoplasms
Neurodegenerative Diseases
English The general functions of lymphatic vessels in fluid transport and immunosurveillance are well recognized. However, accumulating evidence indicates that lymphatic vessels play active and versatile roles in a tissue- and organ-specific manner during homeostasis and in multiple disease processes. This Review discusses recent advances to understand previously unidentified functions of adult mammalian lymphatic vessels, including immunosurveillance and immunomodulation upon pathogen invasion, transport of dietary fat, drainage of cerebrospinal fluid and aqueous humor, possible contributions toward neurodegenerative and neuroinflammatory diseases, and response to anticancer therapies.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://sonar.ch/global/documents/84733
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