Drosophila Myc.
- Gallant P Zoologisches Institut, Universität Zürich, Winterthurerstrasse 190, 8057 Zürich, Switzerland.
- 2009-10-27
Published in:
- Advances in cancer research. - 2009
Animals
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
Diptera
Drosophila Proteins
Drosophila melanogaster
Gene Regulatory Networks
Genes, myc
Proto-Oncogene Proteins c-myc
Transcription Factors
English
Myc genes play a major role in human cancer, and they are important regulators of growth and proliferation during normal development. Despite intense study over the last three decades, many aspects of Myc function remain poorly understood. The identification of a single Myc homolog in the model organism Drosophila melanogaster more than 10 years ago has opened new possibilities for addressing these issues. This review summarizes what the last decade has taught us about Myc biology in the fruit fly.
- Language
-
- English
- Open access status
- green
- Identifiers
-
- DOI 10.1016/S0065-230X(09)03005-X
- PMID 19854354
- Persistent URL
- https://sonar.ch/global/documents/85347
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