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Treatment of chronic non-infectious uveitis and scleritis.

  • Rossi DC Jules-Gonin Eye Hospital, Fondation Asile des Aveugles, Ophthalmology Department, University of Lausanne, Switzerland.
  • Ribi C Division of Immunology and Allergy, Centre Hospitalier Universitaire Vaudois CHUV, Lausanne, Switzerland.
  • Guex-Crosier Y Jules-Gonin Eye Hospital, Fondation Asile des Aveugles, Ophthalmology Department, University of Lausanne, Switzerland.
  • 2019-03-11
Published in:
  • Swiss medical weekly. - 2019
Adrenal Cortex Hormones
Azathioprine
Cyclosporine
Enzyme Inhibitors
Immunosuppressive Agents
Methotrexate
Mycophenolic Acid
Scleritis
Uveitis
English Ocular inflammations such as uveitis and scleritis can lead to significant visual impairment if not treated properly. To limit potentially sight-threatening complications, good control of the inflammation in the acute phase is necessary. Corticosteroids have been the mainstay of ocular therapies for many years, but high doses of corticosteroids, which are required to maintain quiescence in severe uveitis, can be associated with many systemic and ocular complications. In order to limit steroid side-effects, classic immunosuppressant and immunobiologic agents have been widely used as steroid-sparing agents. In this review, we summarise the immunosuppressive drug therapy utilised in the treatment of ocular inflammatory diseases.
Language
  • English
Open access status
gold
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https://sonar.ch/global/documents/86242
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