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International consensus report on the investigation and management of primary immune thrombocytopenia

  • Provan, Drew Department of Haematology, Barts and The London School of Medicine and Dentistry, London, United Kingdom;
  • Stasi, Roberto Department of Haematology, St George's Healthcare, National Health Service (NHS) Trust, London, United Kingdom;
  • Newland, Adrian C. Department of Haematology, Barts and The London School of Medicine and Dentistry, London, United Kingdom;
  • Blanchette, Victor S. Division of Haematology/Oncology, University of Toronto, The Hospital for Sick Children, Toronto, ON;
  • Bolton-Maggs, Paula Department of Clinical Haematology, Manchester Royal Infirmary, Manchester, United Kingdom;
  • Bussel, James B. Department of Pediatrics, New York Hospital, New York, NY;
  • Chong, Beng H. St George Clinical School, University of New South Wales, Sydney, Australia;
  • Cines, Douglas B. Department of Pathology and Laboratory, Hospital of the University of Pennsylvania, Philadelphia;
  • Gernsheimer, Terry B. Puget Sound Blood Center and The University of Washington, Seattle;
  • Godeau, Bertrand Service de Médecine Interne, Assistance-Publique Hôpitaux de Paris, Paris, France;
  • Grainger, John Royal Manchester Children's Hospital, Manchester, United Kingdom;
  • Greer, Ian Hull York Medical School, University of York, York, United Kingdom;
  • Hunt, Beverley J. Thrombosis & Haemostasis, King's College, London, and Departments of Haematology, Pathology, and Rheumatology, Guy's & St Thomas' National Health Service (NHS) Foundation Trust, London, United Kingdom;
  • Imbach, Paul A. University Children's Hospital, Basel, Switzerland;
  • Lyons, Gordon Obstetric Anaesthesia, St James' University Hospital, Leeds, United Kingdom;
  • McMillan, Robert The Scripps Research Institute, La Jolla, CA;
  • Rodeghiero, Francesco Department of Cell Therapy and Hematology, San Bortolo Hospital, Vicenza, Italy;
  • Sanz, Miguel A. Department of Haematology, Hospital Universitario La Fe, Valencia, Spain;
  • Tarantino, Michael Comprehensive Bleeding Disorders Center, Peoria, IL;
  • Watson, Shirley ITP Support Association, Bedford, United Kingdom;
  • Young, Joan Platelet Disorder Support Association, Rockville, MD; and
  • Kuter, David J. Department of Hematology, Massachusetts General Hospital and Harvard Medical School, Boston
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Published in:
  • Blood. - American Society of Hematology. - 2010, vol. 115, no. 2, p. 168-186
Immunology
Cell Biology
Biochemistry
Hematology
English AbstractPreviously published guidelines for the diagnosis and management of primary immune thrombocytopenia (ITP) require updating largely due to the introduction of new classes of therapeutic agents, and a greater understanding of the disease pathophysiology. However, treatment-related decisions still remain principally dependent on clinical expertise or patient preference rather than high-quality clinical trial evidence. This consensus document aims to report on new data and provide consensus-based recommendations relating to diagnosis and treatment of ITP in adults, in children, and during pregnancy. The inclusion of summary tables within this document, supported by information tables in the online appendices, is intended to aid in clinical decision making.
Language
  • English
Open access status
green
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https://sonar.ch/global/documents/92274
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