Predicting CYP3A-mediated midazolam metabolism in critically ill neonates, infants, children and adults with inflammation and organ failure

Brussee, Janneke M. ORCID Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research (LACDR); Leiden University; Leiden The Netherlands
Vet, Nienke J. Department of Pediatrics; Erasmus MC - Sophia Children's Hospital; Rotterdam The Netherlands
Krekels, Elke H. J. Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research (LACDR); Leiden University; Leiden The Netherlands
Valkenburg, Abraham J. Intensive Care and Department of Pediatric Surgery; Erasmus MC - Sophia Children's Hospital; Rotterdam The Netherlands
Jacqz-Aigrain, Evelyne ORCID Department of Pediatric Pharmacology and Pharmacogenetics; Hôpital Robert Debré; Paris France
van Gerven, Joop M. A. Centre for Human Drug Research; Leiden The Netherlands
Swart, Eleonora L. Department of Clinical Pharmacology and Pharmacy; VU University Medical Centre; Amsterdam The Netherlands
van den Anker, Johannes N. Division of Clinical Pharmacology; Children's National Health System; Washington DC USA
Tibboel, Dick Department of Pediatrics; Erasmus MC - Sophia Children's Hospital; Rotterdam The Netherlands
de Hoog, Matthijs Department of Pediatrics; Erasmus MC - Sophia Children's Hospital; Rotterdam The Netherlands
de Wildt, Saskia N. Department of Pharmacology and Toxicology; Radboud University Medical Centre; Nijmegen The Netherlands
Knibbe, Catherijne A. J. Department of Clinical Pharmacy; St Antonius Hospital; Nieuwegein The Netherlands

Published in:

British Journal of Clinical Pharmacology. - Wiley. - 2017, vol. 84, no. 2, p. 358-368

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hybrid

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https://sonar.ch/global/documents/92703

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