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Partially dissociable roles of OFC and ACC in stimulus-guided and action-guided decision making.

  • Khani A Visual Cognition Laboratory, Department of Medicine, University of Fribourg, Fribourg, Switzerland; and Center for Cognition, University of Fribourg, Fribourg, Switzerland.
  • 2014-01-10
Published in:
  • Journal of neurophysiology. - 2014
action
anterior cingulate cortex
decision making
dissociation
orbitofrontal cortex
outcome
single neuron
stimulus
Animals
Decision Making
Gyrus Cinguli
Humans
Neurons
Prefrontal Cortex
English Recently, the functional specialization of prefrontal areas of the brain, and, specifically, the functional dissociation of the orbitofrontal cortex (OFC) and the anterior cingulate cortex (ACC), during decision making have become a particular focus of research. A number of neuropsychological and lesion studies have shown that the OFC and ACC have dissociable functions in various dimensions of decision making, which are supported by their different anatomical connections. A recent single-neuron study, however, described a more complex picture of the functional dissociation between these two frontal regions during decision making. Here, I discuss the results of that study and consider alternative interpretations in connection with other findings.
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  • English
Open access status
green
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https://sonar.ch/global/documents/92908
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