"Noninfective Endocarditis": A Case Report of Hereditary Coagulation Disorders in a 28-Year-Old Male.
- Reid G Department of Cardiac Surgery, University Hospital Basel, 4031 Basel, Switzerland.
- Koechlin L Department of Cardiac Surgery, University Hospital Basel, 4031 Basel, Switzerland.
- Reuthebuch O Department of Cardiac Surgery, University Hospital Basel, 4031 Basel, Switzerland.
- Rüter F Department of Cardiac Surgery, University Hospital Basel, 4031 Basel, Switzerland.
- Hopfer H Institute of Medical Genetics and Pathology, University Hospital Basel, 4031 Basel, Switzerland.
- Eckstein F Department of Cardiac Surgery, University Hospital Basel, 4031 Basel, Switzerland.
- Santer D Department of Cardiac Surgery, University Hospital Basel, 4031 Basel, Switzerland.
- 2020-06-12
Published in:
- Diagnostics (Basel, Switzerland). - 2020
English
We report a case of a young male who presented with acute limb ischemia after sport. With no prior history of disease, a non-infective endocarditis of the native aortic valve was diagnosed. After surgical valve replacement, the patient suffered from acute myocardial ischemia under phenprocoumon therapy. Anti-coagulant monitoring was subsequently changed to Factor II analysis after a rare Factor VII deficiency and prothrombin mutation (G20210A) was diagnosed.
- Language
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- English
- Open access status
- gold
- Identifiers
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- DOI 10.3390/diagnostics10060384
- PMID 32521783
- Persistent URL
- https://sonar.ch/global/documents/93521
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