Synovial fibroblasts in 2017.
- Ospelt C Department of Rheumatology, Center of Experimental Rheumatology, University Hospital and University of Zurich, Zurich, Switzerland.
- 2017-10-31
Published in:
- RMD open. - 2017
English
Stromal cells like synovial fibroblasts gained great interest over the years, since it has become clear that they strongly influence their environment and neighbouring cells. The current review describes the role of synovial fibroblasts as cells of the innate immune system and expands on their involvement in inflammation and cartilage destruction in rheumatoid arthritis (RA). Furthermore, epigenetic changes in RA synovial fibroblasts and studies that focused on the identification of different subsets of synovial fibroblasts are discussed.
- Language
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- English
- Open access status
- gold
- Identifiers
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- DOI 10.1136/rmdopen-2017-000471
- PMID 29081987
- Persistent URL
- https://sonar.ch/global/documents/94434
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