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Journal article

Genome sequence of the progenitor of the wheat D genome Aegilops tauschii.

  • Luo MC Department of Plant Sciences, University of California, Davis, California, USA.
  • Gu YQ Crop Improvement & Genetics Research, USDA-ARS, Albany, California USA.
  • Puiu D Center for Computational Biology, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Wang H Institute of Plant Breeding, Genetics and Genomics, Department of Crop & Soil Sciences, University of Georgia, Athens, Georgia, USA.
  • Twardziok SO Plant Genome and Systems Biology, Helmholtz Zentrum München, Neuherberg, Germany.
  • Deal KR Department of Plant Sciences, University of California, Davis, California, USA.
  • Huo N Department of Plant Sciences, University of California, Davis, California, USA.
  • Zhu T Department of Plant Sciences, University of California, Davis, California, USA.
  • Wang L Department of Plant Sciences, University of California, Davis, California, USA.
  • Wang Y Department of Plant Sciences, University of California, Davis, California, USA.
  • McGuire PE Department of Plant Sciences, University of California, Davis, California, USA.
  • Liu S Department of Plant Sciences, University of California, Davis, California, USA.
  • Long H Department of Plant Sciences, University of California, Davis, California, USA.
  • Ramasamy RK Department of Plant Sciences, University of California, Davis, California, USA.
  • Rodriguez JC Department of Plant Sciences, University of California, Davis, California, USA.
  • Van SL Department of Plant Sciences, University of California, Davis, California, USA.
  • Yuan L Department of Plant Sciences, University of California, Davis, California, USA.
  • Wang Z Department of Plant Sciences, University of California, Davis, California, USA.
  • Xia Z Department of Plant Sciences, University of California, Davis, California, USA.
  • Xiao L Department of Plant Sciences, University of California, Davis, California, USA.
  • Anderson OD Crop Improvement & Genetics Research, USDA-ARS, Albany, California USA.
  • Ouyang S Crop Improvement & Genetics Research, USDA-ARS, Albany, California USA.
  • Liang Y Crop Improvement & Genetics Research, USDA-ARS, Albany, California USA.
  • Zimin AV Center for Computational Biology, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Pertea G Center for Computational Biology, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Qi P Institute of Plant Breeding, Genetics and Genomics, Department of Crop & Soil Sciences, University of Georgia, Athens, Georgia, USA.
  • Bennetzen JL Department of Genetics, University of Georgia, Athens, Georgia, USA.
  • Dai X Department of Statistics, University of California, Davis, California, USA.
  • Dawson MW Department of Statistics, University of California, Davis, California, USA.
  • Müller HG Department of Statistics, University of California, Davis, California, USA.
  • Kugler K Plant Genome and Systems Biology, Helmholtz Zentrum München, Neuherberg, Germany.
  • Rivarola-Duarte L Plant Genome and Systems Biology, Helmholtz Zentrum München, Neuherberg, Germany.
  • Spannagl M Plant Genome and Systems Biology, Helmholtz Zentrum München, Neuherberg, Germany.
  • Mayer KFX Plant Genome and Systems Biology, Helmholtz Zentrum München, Neuherberg, Germany.
  • Lu FH Department Cell and Developmental Biology, John Innes Centre, Norwich Research Park, Norwich, UK.
  • Bevan MW Department Cell and Developmental Biology, John Innes Centre, Norwich Research Park, Norwich, UK.
  • Leroy P INRA, UBP, UMR 1095, GDEC, Clermont-Ferrand, France.
  • Li P Agriculture & Agri-Food Canada, Morden, Winnipeg, Canada.
  • You FM Agriculture & Agri-Food Canada, Morden, Winnipeg, Canada.
  • Sun Q China Agricultural University, Beijing, China.
  • Liu Z China Agricultural University, Beijing, China.
  • Lyons E CyVerse, University of Arizona, Tucson, Arizona, USA.
  • Wicker T Department of Plant and Microbial Biology, University of Zürich, Zürich, Switzerland.
  • Salzberg SL Center for Computational Biology, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Devos KM Institute of Plant Breeding, Genetics and Genomics, Department of Crop & Soil Sciences, University of Georgia, Athens, Georgia, USA.
  • Dvořák J Department of Plant Sciences, University of California, Davis, California, USA.
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  • 2017-11-17
Published in:
  • Nature. - 2017
English Aegilops tauschii is the diploid progenitor of the D genome of hexaploid wheat (Triticum aestivum, genomes AABBDD) and an important genetic resource for wheat. The large size and highly repetitive nature of the Ae. tauschii genome has until now precluded the development of a reference-quality genome sequence. Here we use an array of advanced technologies, including ordered-clone genome sequencing, whole-genome shotgun sequencing, and BioNano optical genome mapping, to generate a reference-quality genome sequence for Ae. tauschii ssp. strangulata accession AL8/78, which is closely related to the wheat D genome. We show that compared to other sequenced plant genomes, including a much larger conifer genome, the Ae. tauschii genome contains unprecedented amounts of very similar repeated sequences. Our genome comparisons reveal that the Ae. tauschii genome has a greater number of dispersed duplicated genes than other sequenced genomes and its chromosomes have been structurally evolving an order of magnitude faster than those of other grass genomes. The decay of colinearity with other grass genomes correlates with recombination rates along chromosomes. We propose that the vast amounts of very similar repeated sequences cause frequent errors in recombination and lead to gene duplications and structural chromosome changes that drive fast genome evolution.
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https://sonar.ch/global/documents/95462
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