Combined molecular lipophilicity descriptors and their role in understanding intramolecular effects.
Journal article

Combined molecular lipophilicity descriptors and their role in understanding intramolecular effects.

  • 1999-08-11
Published in:
  • Pharmaceutical science & technology today. - 1999
English Traditional lipophilicity parameters (log P and log D) are well-known physico-chemical descriptors largely used in QSAR studies. Besides their numerical value, log P data contain a variety of information about inter- and intramolecular forces affecting partitioning and its related biological phenomena. The deconvolution of information from log P can be accessed only by adequate interpretative tools, such as new lipophilic-combined descriptors, of which features and some applications are presented in this review.
Language
  • English
Open access status
closed
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Persistent URL
https://sonar.ch/global/documents/981
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