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Free jejunum transfers for functional reconstruction after tumour resections in the oral cavity and the pharynx: changes of morphology and function.
Journal article

Free jejunum transfers for functional reconstruction after tumour resections in the oral cavity and the pharynx: changes of morphology and function.

  • 1996-01-01
Published in:
  • Microsurgery. - 1996
Carcinoma, Squamous Cell
Female
Fibrosis
Head and Neck Neoplasms
Humans
Hypopharyngeal Neoplasms
Jejunum
Male
Middle Aged
Reconstructive Surgical Procedures
Retrospective Studies
Transplantation, Autologous
Treatment Outcome
English Oropharyngeal reconstruction following resections for locally advanced carcinoma by free jejunum transfer was studied in 31 consecutive cases over a period of 6 years, from 1988-1994. The most common site was the hypopharynx (n = 23). Reconstruction of the tonsillar region was performed in 5 cases and of the inner lining of the mouth in 5 cases. Two patients underwent neoglottic reconstruction, creating a tracheo-pharyngeal shunt. By use of an exteriorized jejunal segment for flap monitoring changes in morphology and function of a microvascular transferred denervated segment of jejunum could be monitored. The success rate was 94%. No evidence of fistula formation and local dehiscence were experienced in this series. Histological examinations showed some fibrotic changes 6 months after transplantation; lubrication and motility of the transplant were not severely altered. Biosynthesis, processing, and proteolytic activity of the jejunal epithelial cells were not impaired 2 weeks postoperatively.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://sonar.ch/global/documents/99123
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