Journal article
Patterning gradients.
- Venkataraman NV Laboratory for Surface Science and Technology, Department of Materials, ETH Zurich, Zurich, Switzerland.
- Cremmel CV Laboratory for Surface Science and Technology, Department of Materials, ETH Zurich, Zurich, Switzerland.
- Zink C Laboratory for Surface Science and Technology, Department of Materials, ETH Zurich, Zurich, Switzerland; Phonak AG, Stäfa, Switzerland.
- Huber RP Laboratory for Surface Science and Technology, Department of Materials, ETH Zurich, Zurich, Switzerland.
- Spencer ND Laboratory for Surface Science and Technology, Department of Materials, ETH Zurich, Zurich, Switzerland.
- 2014-01-21
Published in:
- Methods in cell biology. - 2014
Cell migration
Gradient fabrication
High-throughput screening
Hydrophilicity
Hydrophobicity
Morphology gradient
Patterning
Roughness
Surface-chemical gradient
Cell Culture Techniques
Gene Expression
High-Throughput Screening Assays
Humans
Surface Properties
English
Surface-chemical and -morphological gradients can be extremely useful in cell-biological research as high-throughput screening tools-for example, exposing a given set of cells to many different surface conditions at once, under identical ambient conditions, in order to monitor cell behavior such as proliferation or specific gene expression. They can also be used to investigate the effects of gradients themselves on cell behavior, such as migration. A number of simple, reliable techniques for both chemical- and morphological-gradient fabrication have been developed in our laboratories and are described in detail in the following.
- Language
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- English
- Open access status
- closed
- Identifiers
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- DOI 10.1016/B978-0-12-416742-1.00006-8
- PMID 24439281
- Persistent URL
- https://sonar.ch/global/documents/180992
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