![[Determination of kidney function in patients with ovarian cancer treated with chemotherapy: calculation versus measurement of creatine clearance].](/static/images/no-image.png)
Journal article
[Determination of kidney function in patients with ovarian cancer treated with chemotherapy: calculation versus measurement of creatine clearance].
- 1994-01-01
Published in:
- Gynakologisch-geburtshilfliche Rundschau. - 1994
Adult
Aged
Antineoplastic Combined Chemotherapy Protocols
Carboplatin
Cisplatin
Creatinine
False Positive Reactions
Female
Humans
Kidney Function Tests
Mathematical Computing
Middle Aged
Ovarian Neoplasms
ROC Curve
English
In patients with ovarian cancer receiving chemotherapy we compared the creatinine clearance measured in the usual way with the calculation of the creatinine clearance according to the formulas of Jelliffe and Cockroft. Regression analysis only showed a moderate correlation, whereas the analysis of the data by ROC curves allows the use of these formulas as screening tests with acceptable values of sensitivity and false-positive rate. Therefore, in the majority of these patients, collecting urine over 24 h before starting chemotherapy is no longer necessary.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1159/000272359
- PMID 7987083
- Persistent URL
- https://sonar.ch/global/documents/185553
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