First documented outbreak of KPC-2-producing Klebsiella pneumoniae in Switzerland: infection control measures and clinical management.
- Lemmenmeier E Division of Infectious Diseases and Infection Control, Department of Internal Medicine, Cantonal Hospital St. Gallen, Rorschacherstrasse 95, 9007, St. Gallen, Switzerland, eva.lemmenmeier@kssg.ch.
- Kohler P
- Bruderer T
- Goldenberger D
- Kleger GR
- Schlegel M
- 2014-01-31
Published in:
- Infection. - 2014
Adult
Aged
Anti-Bacterial Agents
Colistin
Disease Outbreaks
Electrophoresis, Gel, Pulsed-Field
Genotype
Humans
Infection Control
Intensive Care Units
Klebsiella Infections
Klebsiella pneumoniae
Male
Meropenem
Middle Aged
Minocycline
Molecular Typing
Switzerland
Tertiary Care Centers
Thienamycins
Tigecycline
Treatment Outcome
beta-Lactamases
English
We report the epidemiological and clinical features of the first outbreak of Klebsiella pneumoniae carbapenemase-producing K. pneumoniae (KPC-KP) type 2 in Switzerland. The outbreak took place in the medical intensive care unit (MICU) of our tertiary care hospital and affected three severely ill patients. After the implementation of strict infection control measures, no further patients colonised with KPC-KP could be detected by the screening of exposed patients. Successful treatment of patients infected with KPC-KP consisted of a combination therapy of meropenem, colistin and tigecycline.
- Language
-
- English
- Open access status
- green
- Identifiers
-
- DOI 10.1007/s15010-013-0578-9
- PMID 24477886
- Persistent URL
- https://sonar.ch/global/documents/186438
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