Budd-Chiari syndrome related to factor V Leiden mutation.

Delarive J; Gonvers JJ

doi:10.1111/j.1572-0241.1998.184_b.x

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Journal article

Budd-Chiari syndrome related to factor V Leiden mutation.

Delarive J University Hospital (CHUV)/University Medical Outpatients Department (PMU), Lausanne, Switzerland.
Gonvers JJ

1998-05-12

Published in:

The American journal of gastroenterology. - 1998

English We here describe a young patient who presented with chronic Budd-Chiari syndrome. An exhaustive etiological investigation to detect a procoagulable state was negative except for factor V mutation (factor V Leiden), a factor associated with resistance to activated protein C. Factor V Leiden is known to be a common, high risk factor for thrombosis. This factor should be routinely investigated in patients with Budd-Chiari syndrome, as factor V Leiden mutation is probably the procoagulable state responsible for many cases of "idiopathic" Budd-Chiari syndrome.

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