Journal article

Common brain disorders are associated with heritable patterns of apparent aging of the brain.

  • Kaufmann T NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway. bias.kaufmann@medisin.uio.no.
  • van der Meer D NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Doan NT NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Schwarz E Department of Psychiatry and Psychotherapy Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
  • Lund MJ NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Agartz I NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Alnæs D NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Barch DM Department of Psychological and Brain Sciences, Washington University in St. Louis, St. Louis, USA.
  • Baur-Streubel R Department of Psychology I, University of Würzburg, Würzburg, Germany.
  • Bertolino A Institute of Psychiatry Bari University Hospital, Bari, Italy.
  • Bettella F NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Beyer MK Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Bøen E Department of Psychiatry Diakonhjemmet Hospital, Oslo, Norway.
  • Borgwardt S Department of Psychiatry (UPK), University of Basel, Basel, Switzerland.
  • Brandt CL NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Buitelaar J Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behaviour Radboud University Medical Center, Nijmegen, The Netherlands.
  • Celius EG Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Cervenka S Centre for Psychiatry Research, Department of Clinical Neuroscience Karolinska Institutet & Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden.
  • Conzelmann A Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy University of Tübingen, Tübingen, Germany.
  • Córdova-Palomera A NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Dale AM Center for Multimodal Imaging and Genetics, University of California at San Diego, La Jolla, CA, USA.
  • de Quervain DJF Division of Cognitive Neuroscience, University of Basel, Basel, Switzerland.
  • Di Carlo P Department of Basic Medical Science, Neuroscience and Sense Organs University of Bari, Bari, Italy.
  • Djurovic S Department of Medical Genetics, Oslo University Hospital, Oslo, Norway.
  • Dørum ES NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Eisenacher S Department of Psychiatry and Psychotherapy Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
  • Elvsåshagen T NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Espeseth T Department of Psychology, University of Oslo, Oslo, Norway.
  • Fatouros-Bergman H Centre for Psychiatry Research, Department of Clinical Neuroscience Karolinska Institutet & Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden.
  • Flyckt L Centre for Psychiatry Research, Department of Clinical Neuroscience Karolinska Institutet & Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden.
  • Franke B Departments of Human Genetics and Psychiatry, Donders Institute for Brain, Cognition and Behaviour Radboud University Medical Center, Nijmegen, The Netherlands.
  • Frei O NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Haatveit B NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Håberg AK Department of Neuromedicine and Movement Science Norwegian, University of Science and Technology, Trondheim, Norway.
  • Harbo HF Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Hartman CA Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
  • Heslenfeld D Clinical Neuropsychology section Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
  • Hoekstra PJ Department of Child and Adolescent Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
  • Høgestøl EA Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Jernigan TL Center for Human Development, University of California, San Diego, USA.
  • Jonassen R Faculty of Health Sciences, Oslo Metropolitan University, Oslo, Norway.
  • Jönsson EG NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Kirsch P Department of Old Age Psychiatry and Psychotic Disorders Medical University of Lodz, Lodz, Poland.
  • Kłoszewska I NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Kolskår KK Department of Psychiatry Diakonhjemmet Hospital, Oslo, Norway.
  • Landrø NI NORMENT, Department of Clinical Science, University of Bergen, Bergen, Norway.
  • Le Hellard S Division of Molecular Psychiatry, Center of Mental Health, University of Würzburg, Würzburg, Germany.
  • Lesch KP Department of Psychiatry, Warneford Hospital University of Oxford, Oxford, UK.
  • Lovestone S Department of Biomedicine, University of Bergen, Bergen, Norway.
  • Lundervold A Department of Biological and Medical Psychology, University of Bergen, Bergen, Norway.
  • Lundervold AJ NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Maglanoc LA Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Malt UF Institute of Gerontology and Geriatrics, University of Perugia, Perugia, Italy.
  • Mecocci P NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Melle I Department of Psychiatry and Psychotherapy Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
  • Meyer-Lindenberg A NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Moberget T NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Norbom LB CatoSenteret Rehabilitation Center Son, Oslo, Norway.
  • Nordvik JE Departments of Radiation Sciences and Integrative Medical Biology, Umeå Center for Functional Brain Imaging Umeå University, Umeå, Sweden.
  • Nyberg L Clinical Neuropsychology section Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
  • Oosterlaan J Department of Basic Medical Science, Neuroscience and Sense Organs University of Bari, Bari, Italy.
  • Papalino M Division of Cognitive Neuroscience, University of Basel, Basel, Switzerland.
  • Papassotiropoulos A Department of Psychology I, University of Würzburg, Würzburg, Germany.
  • Pauli P Department of Basic Medical Science, Neuroscience and Sense Organs University of Bari, Bari, Italy.
  • Pergola G Department of Geriatric Medicine, Oslo University Hospital, Oslo, Norway.
  • Persson K NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Richard G NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Rokicki J NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Sanders AM Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Selbæk G NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Shadrin AA NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Smeland OB Department of Neurology, Institute of Clinical Medicine University of Eastern Finland, Kuopio, Finland.
  • Soininen H Division of Radiology and Nuclear Medicine, Section of Neuroradiology Oslo University Hospital, Oslo, Norway.
  • Sowa P NORMENT, Department of Clinical Science, University of Bergen, Bergen, Norway.
  • Steen VM 1st Department of Neurology Aristotle University of Thessaloniki, Thessaloniki, Greece.
  • Tsolaki M NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Ulrichsen KM UMR Inserm 1027, CHU Toulouse, UPS, Toulouse, France.
  • Vellas B Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
  • Wang L Department of Psychiatry, Psychosomatics and Psychotherapy University of Lübeck, Lübeck, Germany.
  • Westman E Division of Molecular Psychiatry, Center of Mental Health, University of Würzburg, Würzburg, Germany.
  • Ziegler GC Department of Psychiatry and Psychotherapy Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
  • Zink M NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Andreassen OA NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway. l.t.westlye@psykologi.uio.no.
  • Westlye LT
Show more…
  • 2019-09-26
Published in:
  • Nature neuroscience. - 2019
English Common risk factors for psychiatric and other brain disorders are likely to converge on biological pathways influencing the development and maintenance of brain structure and function across life. Using structural MRI data from 45,615 individuals aged 3-96 years, we demonstrate distinct patterns of apparent brain aging in several brain disorders and reveal genetic pleiotropy between apparent brain aging in healthy individuals and common brain disorders.
Language
  • English
Open access status
green
Identifiers
Persistent URL
https://sonar.ch/global/documents/202949
Statistics

Document views: 77 File downloads:
  • Full-text: 0