Osteoarthritis: Small studies overestimate the benefit of therapies for OA.

Finckh A; Tramèr MR

doi:10.1038/nrrheum.2010.162

Back

Journal article

Osteoarthritis: Small studies overestimate the benefit of therapies for OA.

Finckh A Division of Rheumatology, University Hospitals of Geneva, Avenue Beau-Séjour 26, CH-1211 Geneva 14, Switzerland. A. Finckhaxel.finckh@hcuge.ch
Tramèr MR

2010-11-02

Published in:

Nature reviews. Rheumatology. - 2010

Randomized Controlled Trials as Topic

English a meta-epidemiological study has revealed that the inclusion of small studies in meta-analyses of osteoarthritis interventions could lead to an overestimation of the benefit of these interventions. Does this mean meta-analyses should be restricted to trials with large sample sizes?

Language