Developmental biology of the pancreas.
- Merino PL Department of Morphology, University of Geneva Medical School, Geneva, Switzerland. Pedro.Herrera@medecine.unige.ch
- 2004-08-04
Published in:
- Cell biochemistry and biophysics. - 2004
Animals
Cell Lineage
Diphtheria Toxin
Gene Expression Regulation, Developmental
Genetic Techniques
Humans
Insulin
Mice
Mice, Transgenic
Models, Biological
Pancreas
Phenotype
Stem Cells
Time Factors
English
In this review, I summarize some aspects of murine pancreas development, with particular emphasis on the analysis of the ontogenetic relationships between different pancreatic cell types. Lineage analyses allow the identification of the progenitor cells from which mature cell types arise. The identification and successful in vitro culture of putative pancreatic stem cells is highly relevant for future cell replacement therapies in diabetic patients.
- Language
-
- English
- Open access status
- green
- Identifiers
-
- DOI 10.1385/cbb:40:3:127
- PMID 15289649
- Persistent URL
- https://sonar.ch/global/documents/230501
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