Nanodentistry: combining nanostructured materials and stem cells for dental tissue regeneration.
- Mitsiadis TA Institute of Oral Biology, Department of Orofacial Development & Regeneration, ZZM, Faculty of Medicine, University of Zurich, Zurich, Switzerland. thimios.mitsiadis@zzm.uzh.ch
- Woloszyk A
- Jiménez-Rojo L
- 2012-12-06
Published in:
- Nanomedicine (London, England). - 2012
Animals
Humans
Nanomedicine
Nanostructures
Regeneration
Regenerative Medicine
Stem Cell Transplantation
Stem Cells
Tissue Engineering
Tissue Scaffolds
Tooth
English
Regenerative dentistry represents an attractive multidisciplinary therapeutic approach that complements traditional restorative/surgery techniques and benefits from recent advances in stem cell biology, molecular biology, genomics and proteomics. Materials science is important in such advances to move regenerative dentistry from the laboratory to the clinic. The design of novel nanostructured materials, such as biomimetic matrices and scaffolds for controlling cell fate and differentiation, and nanoparticles for diagnostics, imaging and targeted treatment, is needed. The combination of nanotechnology, which allows the creation of sophisticated materials with exquisite fine structural detail, and stem cell biology turns out to be increasingly useful in regenerative medicine. The administration to patients of dynamic biological agents comprising stem cells, bioactive scaffolds and/or nanoparticles will certainly increase the regenerative impact of dental pathological tissues. This overview briefly describes some of the actual benefits and future possibilities of nanomaterials in the emerging field of stem cell-based regenerative dentistry.
- Language
-
- English
- Open access status
- green
- Identifiers
-
- DOI 10.2217/nnm.12.146
- PMID 23210714
- Persistent URL
- https://sonar.ch/global/documents/263030
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