Journal article
Prevalence and Progression of Lower Urinary Tract Symptoms in an Aging Population.
- Rohrmann S Division of Chronic Disease Epidemiology, Epidemiology, Biostatistics and Prevention Institute (EBPI), University of Zurich, Zurich, Switzerland. Electronic address: sabine.rohrmann@uzh.ch.
- Katzke V Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
- Kaaks R Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
- 2016-06-28
Published in:
- Urology. - 2016
Age Factors
Aged
Disease Progression
Humans
Lower Urinary Tract Symptoms
Male
Middle Aged
Prevalence
Prospective Studies
Time Factors
English
OBJECTIVE
To examine the prevalence of lower urinary tract symptoms (LUTS) in males of the general population.
MATERIALS AND METHODS
In our analysis, we included 8627 men, 48-79 years of age, who participated in the fourth follow-up (FUP) of EPIC-Heidelberg (2007-2009) and replied to questions on LUTS. According to the International Prostate Symptom Score questionnaire, men were categorized as having mild (0-7 points), moderate (8-19 points), or severe LUTS (20-35 points). In addition, we examined progression of LUTS among 7821 men, who also participated in FUP 5 (2010-2012).
RESULTS
There were 75.3% of men who reported mild, 22.0% who reported moderate, and 2.7% who reported severe LUTS. The prevalence increased with age. At FUP 4, 5.8% (mild symptoms) to 39.7% (severe LUTS) of participants reported use of any type of benign prostatic hyperplasia or LUTS medication. Nocturia, that is, getting up at night at least twice, was the most common symptom, followed by incomplete emptying of the bladder and urgency. There were 54.8% of men who reported worse LUTS in FUP 5, but 27.1% reported an improvement in symptoms.
CONCLUSION
About a quarter of middle-aged and elderly men reported clinically relevant LUTS. Whereas symptoms in some men actually improve, more than half of men experience worsening of symptoms over a 3-year period in time.
To examine the prevalence of lower urinary tract symptoms (LUTS) in males of the general population.
MATERIALS AND METHODS
In our analysis, we included 8627 men, 48-79 years of age, who participated in the fourth follow-up (FUP) of EPIC-Heidelberg (2007-2009) and replied to questions on LUTS. According to the International Prostate Symptom Score questionnaire, men were categorized as having mild (0-7 points), moderate (8-19 points), or severe LUTS (20-35 points). In addition, we examined progression of LUTS among 7821 men, who also participated in FUP 5 (2010-2012).
RESULTS
There were 75.3% of men who reported mild, 22.0% who reported moderate, and 2.7% who reported severe LUTS. The prevalence increased with age. At FUP 4, 5.8% (mild symptoms) to 39.7% (severe LUTS) of participants reported use of any type of benign prostatic hyperplasia or LUTS medication. Nocturia, that is, getting up at night at least twice, was the most common symptom, followed by incomplete emptying of the bladder and urgency. There were 54.8% of men who reported worse LUTS in FUP 5, but 27.1% reported an improvement in symptoms.
CONCLUSION
About a quarter of middle-aged and elderly men reported clinically relevant LUTS. Whereas symptoms in some men actually improve, more than half of men experience worsening of symptoms over a 3-year period in time.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1016/j.urology.2016.06.021
- PMID 27346671
- Persistent URL
- https://sonar.ch/global/documents/263542
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