Journal article
Coxiella burnetii vascular graft infection.
- Senn L Infectious Diseases Service, Department of Internal Medicine, University Hospital, Lausanne, Switzerland. Laurence.Senn@chuv.ch
- Franciolli M
- Raoult D
- Moulin A
- Von Segesser L
- Calandra T
- Greub G
- 2005-12-13
Published in:
- BMC infectious diseases. - 2005
Antibodies, Bacterial
Aorta, Abdominal
Aortic Aneurysm, Abdominal
Blood Vessel Prosthesis
Chloroquine
Coxiella burnetii
Doxycycline
Femoral Artery
Humans
Male
Middle Aged
Polymerase Chain Reaction
Prosthesis-Related Infections
Q Fever
RNA, Ribosomal, 16S
Treatment Outcome
English
BACKGROUND
Coxiella burnetii, the causative agent of Q fever, may cause culture-negative vascular graft infections. Very few cases of C. burnetii infection of a vascular graft have been reported. All were diagnosed by serology.
CASE PRESENTATION
We report the first case of Coxiella burnetii vascular graft infection diagnosed by broad-range PCR and discuss the diagnostic approaches and treatment strategies of chronic C. burnetii infection.
CONCLUSION
C. burnetii should be considered as etiological agent in patients with a vascular graft and fever, abdominal pain, and laboratory signs of inflammation, with or without exposure history. Broad-range PCR should be performed on culture-negative surgical samples in patients with suspected infection of vascular graft.
Coxiella burnetii, the causative agent of Q fever, may cause culture-negative vascular graft infections. Very few cases of C. burnetii infection of a vascular graft have been reported. All were diagnosed by serology.
CASE PRESENTATION
We report the first case of Coxiella burnetii vascular graft infection diagnosed by broad-range PCR and discuss the diagnostic approaches and treatment strategies of chronic C. burnetii infection.
CONCLUSION
C. burnetii should be considered as etiological agent in patients with a vascular graft and fever, abdominal pain, and laboratory signs of inflammation, with or without exposure history. Broad-range PCR should be performed on culture-negative surgical samples in patients with suspected infection of vascular graft.
- Language
-
- English
- Open access status
- gold
- Identifiers
-
- DOI 10.1186/1471-2334-5-109
- PMID 16336642
- Persistent URL
- https://sonar.ch/global/documents/264461
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