Journal article
Muscle psoas indices measured by ultrasound in cirrhosis - Preliminary evaluation of sarcopenia assessment and prediction of liver decompensation and mortality.
- Hari A Faculty of Medicine, University of Ljubljana, Slovenia. Electronic address: andrej.hari@sb-celje.si.
- Berzigotti A Swiss Liver Center, Hepatology, University Clinic for Visceral Surgery and Medicine, Inselspital, University of Berne, Switzerland.
- Štabuc B Department of Gastroenterology, University Clinic Ljubljana, Slovenia.
- Caglevič N Department of Gastroenterology, General Hospital Celje, Slovenia.
- 2019-09-25
Published in:
- Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver. - 2019
Muscle mass loss
Non-invasive diagnosis
Psoas muscle index
Psoas to height ratio
Adult
Aged
Female
Hospitalization
Humans
Linear Models
Liver Cirrhosis
Logistic Models
Male
Middle Aged
Organ Size
Psoas Muscles
Retrospective Studies
Sarcopenia
Slovenia
Tomography, X-Ray Computed
Ultrasonography
English
BACKGROUND
No data on the European population exists regarding the use of an ultrasoundbased measurement of psoas diameter for sarcopenia assessment in cirrhosis.
AIMS
To determine the applicability of an ultrasound measurement of the psoas muscle diameter in patients with decompensated liver cirrhosis and to assess whether this surrogate is associated with hospitalization due to decompensation and mortality.
METHODS
In 75 consecutive patients with decompensated liver cirrhosis and in 20 control subjects (January 2016 to November 2017), psoas muscle diameter was prospectively measured. The reliable measurements were used for the further analysis. Relevant clinical and laboratory data was collected.
RESULTS
Ultrasound measurement was applicable in 100% of control and in 72% of study subjects. Psoas to height ratio was significantly related to hospitalization and mortality (p < 0.0001, HR 0.717, 95% CI: 0.622-0.828 and p = 0.022; HR = 0.825, 95% CI: 0.701-0.973) as was psoas muscle index (p < 0.0001, HR = 0.881, 95% CI: 0.836-0.929 and p = 0.017; HR = 0.930, 95% CI: 0.876-0.987).
CONCLUSIONS
Ultrasound measurement of psoas muscle diameter and its derived indices is applicable and associated with hospitalization and mortality in patients with decompensated liver cirrhosis.
No data on the European population exists regarding the use of an ultrasoundbased measurement of psoas diameter for sarcopenia assessment in cirrhosis.
AIMS
To determine the applicability of an ultrasound measurement of the psoas muscle diameter in patients with decompensated liver cirrhosis and to assess whether this surrogate is associated with hospitalization due to decompensation and mortality.
METHODS
In 75 consecutive patients with decompensated liver cirrhosis and in 20 control subjects (January 2016 to November 2017), psoas muscle diameter was prospectively measured. The reliable measurements were used for the further analysis. Relevant clinical and laboratory data was collected.
RESULTS
Ultrasound measurement was applicable in 100% of control and in 72% of study subjects. Psoas to height ratio was significantly related to hospitalization and mortality (p < 0.0001, HR 0.717, 95% CI: 0.622-0.828 and p = 0.022; HR = 0.825, 95% CI: 0.701-0.973) as was psoas muscle index (p < 0.0001, HR = 0.881, 95% CI: 0.836-0.929 and p = 0.017; HR = 0.930, 95% CI: 0.876-0.987).
CONCLUSIONS
Ultrasound measurement of psoas muscle diameter and its derived indices is applicable and associated with hospitalization and mortality in patients with decompensated liver cirrhosis.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1016/j.dld.2019.08.017
- PMID 31547952
- Persistent URL
- https://sonar.ch/global/documents/279092
Statistics
Document views: 28
File downloads: