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Journal article

Model systems for regeneration: zebrafish.

  • Marques IJ Institute of Anatomy, University of Bern, Bern 3012, Switzerland.
  • Lupi E Institute of Anatomy, University of Bern, Bern 3012, Switzerland.
  • Mercader N Institute of Anatomy, University of Bern, Bern 3012, Switzerland nadia.mercader@ana.unibe.ch.
  • 2019-09-22
Published in:
  • Development (Cambridge, England). - 2019
Cell progenitors
Genetic tools
Injury methods
Regeneration
Zebrafish
Animals
Drug Evaluation, Preclinical
Genetic Techniques
Humans
Models, Animal
Organogenesis
Regeneration
Zebrafish
English Tissue damage can resolve completely through healing and regeneration, or can produce permanent scarring and loss of function. The response to tissue damage varies across tissues and between species. Determining the natural mechanisms behind regeneration in model organisms that regenerate well can help us develop strategies for tissue recovery in species with poor regenerative capacity (such as humans). The zebrafish (Danio rerio) is one of the most accessible vertebrate models to study regeneration. In this Primer, we highlight the tools available to study regeneration in the zebrafish, provide an overview of the mechanisms underlying regeneration in this system and discuss future perspectives for the field.
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  • English
Open access status
hybrid
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Persistent URL
https://sonar.ch/global/documents/279109
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