Journal article
Infective Endocarditis Following Transcatheter Aortic Valve Replacement: Comparison of Balloon- Versus Self-Expandable Valves.
- Regueiro A Quebec Heart & Lung Institute, Laval University, Quebec City, Canada
- Linke Heart Center, Leipzig University, Germany
- Latib Interventional Cardiology Unit, Ospedale San Raffaele, Milan, Italy
- Ihlemann Righospitalet, Copenhagen, Denmark
- Urena Bichat Hôpital, Paris, France
- Walther Kerckhoff Klinik, Nauheim, Germany
- Husser Deutsches Herzzentrum, München, Germany
- Herrmann C Hospital of the University of Pennsylvania, Philadelphia
- Nombela-Franco Cardiovascular Institute, Hospital Universitario Clinico San Carlos, Madrid, Spain
- Cheema Division of Cardiology, St. Michaels Hospital, Toronto, Canada
- Le Breton H Centre Hospitalier Universitaire de Rennes, France
- Stortecky Bern University Hospital (on behalf of Swiss Registry Centres), Switzerland
- Kapadia Cleveland Clinic
- Bartorelli L Centro Cardiologico Monzino, Milan, Italy
- Sinning Heart Center Bonn, Germany
- Amat-Santos Hospital Clinico Universitario de Valladolid, Spain
- Munoz-Garcia J Department of Cardiology, Hospital Universitario Virgen de la Victoria, Malaga, Spain
- Lerakis Emory University School of Medicine, Atlanta
- Gutíerrez-Ibanes Department of Cardiology, Instituto de Investigación Sanitaria Gregorio Marañon, Hospital Gregorio Maranon, Madrid, Spain
- Abdel-Wahab Heart Center, Bad Segeberg, Germany
- Tchetche Clinique Pasteur, Toulouse, France
- Testa IRCCS Pol. San Donato, Milan, Italy
- Eltchaninoff Hôpital Charles Nicolle, University of Rouen, France
- Livi AOU Santa Maria della Misericordia, Udine, Italy
- Castillo Department of Cardiology, Hospital Universitario Reina Sofia, Cordoba, Spain
- Jilaihawi Cedars-Sinai Heart Institute, Los Angeles
- Webb G Center for Heart Valve Innovation, St. Pauls Hospital, Vancouver, Canada
- Barbanti M Ferrarotto Hospital, Catania, Italy
- Kodali Columbia University Medical Center, New York
- de Brito Jr S Hospital Israelita Albert Einstein, Sao Paulo, Brazil
- Ribeiro B Instituto Nacional Cardiovascular (INCOR), Sao Paulo, Brazil
- Miceli Fondazione Toscana G. Monasterio, Massa, Italy
- Fiorina Ospedali Civili di Brescia, Italy
- Actis Dato Ospedali Mauriziano, Torino, Italy
- Rosato F S. Cocre e Carle Cuneo, Italy
- Serra Hospital Vall d’Hebron, Barcelona, Spain
- Masson Centre Hospitalier de l’Universite de Montreal, Canada
- Wijeysundera C Sunnybrook Health Science Center, Toronto, Canada
- Mangione A Hospital Beneficencia Portuguesa, Sao Paulo, Brazil
- Ferreira Hospital Naval Marcilio Dias, Rio de Janeiro, Brazil
- Lima C Hospital Sao FranciscoSanta Clara, Porto Alegre, Brazil
- Carvalho A Hospital Pró-cardíaco, Rio de Janeiro, Brazil
- Abizaid Instituto Dante Pazzanese de Cardiologia, Sao Paulo, Brazil
- Marino A Hospital Madre Teresa, Belo Horizonte, Brazil
- Esteves Hospital Sao Luiz, Sao Paulo, Brazil
- Andrea C.M. Clínica Sao Vicente, Rio de Janeiro, Brazil
- Messika-Zeitoun Bichat Hôpital, Paris, France
- Himbert Bichat Hôpital, Paris, France
- Kim Kerckhoff Klinik, Nauheim, Germany
- Pellegrini Deutsches Herzzentrum, München, Germany
- Auffret Centre Hospitalier Universitaire de Rennes, France
- Nietlispach University Hospital Zurich, Switzerland
- Pilgrim Bern University Hospital (on behalf of Swiss Registry Centres), Switzerland
- Durand Hôpital Charles Nicolle, University of Rouen, France
- Lisko Emory University School of Medicine, Atlanta
- Makkar R Cedars-Sinai Heart Institute, Los Angeles
- Lemos Instituto Nacional Cardiovascular (INCOR), Sao Paulo, Brazil
- Leon B Columbia University Medical Center, New York
- Puri Quebec Heart & Lung Institute, Laval University, Quebec City, Canada
- San Roman Hospital Clinico Universitario de Valladolid, Spain
- Vahanian Bichat Hôpital, Paris, France
- Søndergaard Righospitalet, Copenhagen, Denmark
- Mangner Heart Center, Leipzig University, Germany
- Rodés-Cabau Quebec Heart & Lung Institute, Laval University, Quebec City, Canada
- 2019-11-08
Published in:
- Circulation. Cardiovascular interventions. - 2019
endocarditis
incidence
registry
transcatheter aortic valve replacement
Aged
Aged, 80 and over
Aortic Valve
Aortic Valve Stenosis
Balloon Valvuloplasty
Clinical Decision-Making
Device Removal
Endocarditis, Bacterial
Female
Heart Valve Prosthesis
Humans
Incidence
Male
Patient Selection
Prosthesis Design
Prosthesis-Related Infections
Registries
Reoperation
Retrospective Studies
Risk Assessment
Risk Factors
Time Factors
Transcatheter Aortic Valve Replacement
Treatment Outcome
English
BACKGROUND
No data exist about the characteristics of infective endocarditis (IE) post-transcatheter aortic valve replacement (TAVR) according to transcatheter valve type. We aimed to determine the incidence, clinical characteristics, and outcomes of patients with IE post-TAVR treated with balloon-expandable valve (BEV) versus self-expanding valve (SEV) systems.
METHODS
Data from the multicenter Infectious Endocarditis After TAVR International Registry was used to compare IE patients with BEV versus SEV.
RESULTS
A total of 245 patients with IE post-TAVR were included (SEV, 47%; BEV, 53%). The timing between TAVR and IE was similar between groups (SEV, 5.5 [1.2-15] months versus BEV, 5.3 [1.7-11.4] months; P=0.89). Enterococcal IE was more frequent in the SEV group (36.5% versus 15.4%; P<0.01), and vegetation location differed according to valve type (stent frame, SEV, 18.6%; BEV, 6.9%; P=0.01; valve leaflet, SEV, 23.9%; BEV, 38.5%; P=0.01). BEV recipients had a higher rate of stroke/systemic embolism (20.0% versus 8.7%, adjusted OR: 2.46, 95% CI: 1.04-5.82, P=0.04). Surgical explant of the transcatheter valve (SEV, 8.7%; BEV, 13.8%; P=0.21), and in-hospital death at the time of IE episode (SEV, 35.6%; BEV, 37.7%; P=0.74) were similar between groups. After a mean follow-up of 13±12 months, 59.1% and 54.6% of the SEV and BEV recipients, respectively, had died (P=0.66).
CONCLUSIONS
The characteristics of IE post-TAVR, including microorganism type, vegetation location, and embolic complications but not early or late mortality, differed according to valve type. These results may help to guide the diagnosis and management of IE and inform future research studies in the field.
No data exist about the characteristics of infective endocarditis (IE) post-transcatheter aortic valve replacement (TAVR) according to transcatheter valve type. We aimed to determine the incidence, clinical characteristics, and outcomes of patients with IE post-TAVR treated with balloon-expandable valve (BEV) versus self-expanding valve (SEV) systems.
METHODS
Data from the multicenter Infectious Endocarditis After TAVR International Registry was used to compare IE patients with BEV versus SEV.
RESULTS
A total of 245 patients with IE post-TAVR were included (SEV, 47%; BEV, 53%). The timing between TAVR and IE was similar between groups (SEV, 5.5 [1.2-15] months versus BEV, 5.3 [1.7-11.4] months; P=0.89). Enterococcal IE was more frequent in the SEV group (36.5% versus 15.4%; P<0.01), and vegetation location differed according to valve type (stent frame, SEV, 18.6%; BEV, 6.9%; P=0.01; valve leaflet, SEV, 23.9%; BEV, 38.5%; P=0.01). BEV recipients had a higher rate of stroke/systemic embolism (20.0% versus 8.7%, adjusted OR: 2.46, 95% CI: 1.04-5.82, P=0.04). Surgical explant of the transcatheter valve (SEV, 8.7%; BEV, 13.8%; P=0.21), and in-hospital death at the time of IE episode (SEV, 35.6%; BEV, 37.7%; P=0.74) were similar between groups. After a mean follow-up of 13±12 months, 59.1% and 54.6% of the SEV and BEV recipients, respectively, had died (P=0.66).
CONCLUSIONS
The characteristics of IE post-TAVR, including microorganism type, vegetation location, and embolic complications but not early or late mortality, differed according to valve type. These results may help to guide the diagnosis and management of IE and inform future research studies in the field.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1161/CIRCINTERVENTIONS.119.007938
- PMID 31694412
- Persistent URL
- https://sonar.ch/global/documents/279157
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