Journal article
Allergic and irritant contact dermatitis to calcipotriol.
- Krayenbühl BH Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.
- Elsner P
- 1999-06-05
Published in:
- American journal of contact dermatitis : official journal of the American Contact Dermatitis Society. - 1999
Administration, Topical
Aged
Calcitriol
Dermatologic Agents
Drug Eruptions
Female
Humans
Middle Aged
Patch Tests
Psoriasis
English
Calcipotriol (Daivonex R; Leo Pharmaceuticals, Zurich, Switzerland) may cause irritation of the skin, whereas allergic reactions are less common. In the present study we describe two patients with different types of reaction patterns, one presenting as an allergic, the other as an irritant contact dermatitis. Irritative skin reactions were observed only at higher testings doses, in contrast to the allergic type of reaction, which occurred at a lower testing dose. The present observation suggests, that a batch of different testing doses, including lower testing doses may help to differentiate between an allergic type of contact dermatitis and an irritant type of reaction after treatment with calcipotriol.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1016/s1046-199x(99)90003-9
- PMID 10357715
- Persistent URL
- https://sonar.ch/global/documents/288825
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