Preconditioning tDCS facilitates subsequent tDCS effect on skill acquisition in older adults.
- Fujiyama H Action and Cognition Laboratory, School of Psychology and Exercise Science, Murdoch University, Perth, Australia; Motor Control Laboratory, KU Leuven, Research Center of Movement Control and Neuroplasticity, Group Biomedical Sciences, Leuven, Belgium. Electronic address: H.Fujiyama@murdoch.edu.au.
- Hinder MR Human Motor Control Laboratory, School of Medicine, University of Tasmania, Hobart, Australia.
- Barzideh A Motor Control Laboratory, KU Leuven, Research Center of Movement Control and Neuroplasticity, Group Biomedical Sciences, Leuven, Belgium.
- Van de Vijver C Motor Control Laboratory, KU Leuven, Research Center of Movement Control and Neuroplasticity, Group Biomedical Sciences, Leuven, Belgium.
- Badache AC Motor Control Laboratory, KU Leuven, Research Center of Movement Control and Neuroplasticity, Group Biomedical Sciences, Leuven, Belgium.
- Manrique-C MN Motor Control Laboratory, KU Leuven, Research Center of Movement Control and Neuroplasticity, Group Biomedical Sciences, Leuven, Belgium.
- Reissig P Human Motor Control Laboratory, School of Medicine, University of Tasmania, Hobart, Australia.
- Zhang X Neural Control of Movement Laboratory, ETH, Zurich, Switzerland.
- Levin O Motor Control Laboratory, KU Leuven, Research Center of Movement Control and Neuroplasticity, Group Biomedical Sciences, Leuven, Belgium.
- Summers JJ Human Motor Control Laboratory, School of Medicine, University of Tasmania, Hobart, Australia; Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK.
- Swinnen SP Motor Control Laboratory, KU Leuven, Research Center of Movement Control and Neuroplasticity, Group Biomedical Sciences, Leuven, Belgium; KU Leuven, Leuven Research Institute for Neuroscience & Disease (LIND), Leuven, Belgium.
- 2016-12-30
Published in:
- Neurobiology of aging. - 2017
Healthy aging
Homeostatic metaplasticity
Primary motor cortex
Skill acquisition
Transcranial direct current stimulation
Adult
Aged
Aging
Conditioning, Psychological
Electric Stimulation
Electrodes
Evoked Potentials, Motor
Female
Humans
Learning
Long-Term Potentiation
Male
Middle Aged
Motor Cortex
Motor Skills
Neural Inhibition
Neuronal Plasticity
Quality of Life
Transcranial Direct Current Stimulation
Transcranial Magnetic Stimulation
Young Adult
English
Functional motor declines that often occur with advancing age-including reduced efficacy to learn new skills-can have a substantial impact on the quality of life. Recent studies using noninvasive brain stimulation indicate that priming the corticospinal system by lowering the threshold for the induction of long-term potentiation-like plasticity before skill training may facilitate subsequent skill learning. Here, we used "priming" protocol, in which we used transcranial direct current stimulation (tDCS) applying the cathode over the primary motor cortex (M1) before the anode placed over M1 during unimanual isometric force control training (FORCEtraining). Older individuals who received tDCS with the cathode placed over M1 before tDCS with the anode placed over M1 concurrent with FORCEtraining showed greater skill improvement and corticospinal excitability increases following the tDCS/FORCEtraining protocol compared with both young and older individuals who did not receive the preceding tDCS with the cathode placed over M1. The results suggested that priming tDCS protocols may be used in clinical settings to improve motor function and thus maintain the functional independence of older adults.
- Language
-
- English
- Open access status
- green
- Identifiers
-
- DOI 10.1016/j.neurobiolaging.2016.11.012
- PMID 28033506
- Persistent URL
- https://sonar.ch/global/documents/36877
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