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Triptans and troponin: a case report.
Journal article

Triptans and troponin: a case report.

  • Weder CR Department of Internal Medicine, University Hospital of Zürich, Rämistrasse 100, CH-8091 Zürich, Switzerland. claudia.weder@usz.ch
  • Schneemann M
  • 2009-06-23
Published in:
  • Orphanet journal of rare diseases. - 2009
Acute Coronary Syndrome
Aged
Electrocardiography
Female
Humans
Migraine Disorders
Piperidines
Serotonin Agents
Treatment Outcome
Troponin T
Tryptamines
English This case report describes for the first time acute coronary syndrome in a 67-year old patient after oral intake of naratriptan for migraine. So far in the literature, only sumatriptan, zolmitriptan and frovatriptan have been described to cause acute coronary syndromes. A 67-year old Swiss woman with thoracic pain after intake of 2.5 mg naratriptan presented with T-wave inversions in the ECG and a positive troponin-T at our hospital. Coronary angiography showed normal coronary arteries. Naratriptan-induced coronary vasospasms were thought to have caused the acute coronary syndrome.Triptans should not be prescribed in patients with pre-existing coronary heart disease. However, triptans can also cause acute coronary syndromes in patients without coronary heart disease--as described in our case report. Severe or persistent thoracic pain after intake of triptans should therefore be investigated accordingly.
Language
  • English
Open access status
gold
Identifiers
Persistent URL
https://sonar.ch/global/documents/4378
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