68Ga-PSMA-11 PET/MR Can Be False Positive in Normal Prostatic Tissue.
- Ferraro DA Department of Nuclear Medicine, University Hospital Zürich, University of Zürich
- Rupp NJ Department of Pathology and Molecular Pathology, University Hospital and University of Zürich
- Donati OF Institute of Diagnostic and Interventional Radiology, University Hospital Zürich
- Messerli M Department of Nuclear Medicine, University Hospital Zürich, University of Zürich
- Eberli D Department of Urology, University Hospital Zürich, University of Zürich, Zürich, Switzerland
- Burger IA Department of Nuclear Medicine, University Hospital Zürich, University of Zürich
- 2019-01-29
Published in:
- Clinical nuclear medicine. - 2019
Aged
Edetic Acid
False Positive Reactions
Humans
Magnetic Resonance Imaging
Male
Multimodal Imaging
Neoplasm Grading
Oligopeptides
Positron-Emission Tomography
Prostate
Prostatic Neoplasms
English
Prostate-specific membrane antigen (PSMA) is a transmembrane glycoprotein expressed in the cytosol of normal prostate tissue and highly overexpressed on the membrane of prostate cancer, therefore increasingly used to image prostate cancer. We report a case of a 65-year-old man with two focal PSMA-positive areas on a Ga-PSMA-11 PET/MR, one corresponding to a prostate carcinoma (Gleason score 4 + 3) and another region without any evidence of malignancy, but with corresponding high PSMA-expression on immunohistochemistry.
- Language
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- English
- Open access status
- green
- Identifiers
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- DOI 10.1097/RLU.0000000000002473
- PMID 30688746
- Persistent URL
- https://sonar.ch/global/documents/47481
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