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Journal article
[Evaluation of correction formulas for tonometry : The Goldmann applanation tonometry in approximation to dynamic contour tonometry].
- Wachtl J Augenklinik, UniversitätsSpital Zürich, Frauenklinikstr. 24, 8091, Zürich, Schweiz.
- Töteberg-Harms M Augenklinik, UniversitätsSpital Zürich, Frauenklinikstr. 24, 8091, Zürich, Schweiz.
- Frimmel S Augenklinik, UniversitätsSpital Zürich, Frauenklinikstr. 24, 8091, Zürich, Schweiz.
- Kniestedt C Augenklinik, UniversitätsSpital Zürich, Frauenklinikstr. 24, 8091, Zürich, Schweiz. kniestedt@tazz.ch.
- 2016-12-07
Published in:
- Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft. - 2017
Correction formula
Dynamic Contour Tonometry
Glaucoma
Goldmann Applanation Tonometry
Intraocular Pressure
Aged
Corneal Pachymetry
Female
Glaucoma
Humans
Male
Mathematics
Middle Aged
Prospective Studies
Reproducibility of Results
Tonometry, Ocular
English
BACKGROUND
Accurate determination of intraocular pressure (IOP) is essential for correct management of glaucoma. Goldmann applanation tonometry (GAT) is the gold standard for measuring IOP despite its limitations due to its dependence on corneal properties. With the aim of improving the accuracy of GAT readings, several correction formulas have been developed.
OBJECTIVE
The aim of this study was to investigate the accuracy and clinical relevance of five correction equations for GAT.
MATERIAL AND METHODS
Prospective study of 112 glaucoma patients at the University Hospital and Talacker Eye Center, Zurich, Switzerland. The IOP was measured with GAT and dynamic contour tonometry (DCT) in randomized order. The GAT readings were adjusted with five correction equations. The primary study endpoint was the degree of concordance between corrected GAT and DCT readings. A discordance of ≥2 mm Hg was defined as significant. The association between discordant IOP measurements and central corneal thickness (CCT) was the secondary study endpoint.
RESULTS
The mean patient age was 66 ± 13 years (60% females and 56% left eyes). The mean IOP was 17.0 mm Hg for GAT and 20.3 mm Hg for DCT, with a discordance of 3.3 mm Hg between GAT und DCT. The discordances between DCT and the corrected values ranged from 2.7 to 5.4 mm Hg. Spearman's rank testing showed a positive correlation between CCT and the discordances of all correction equations and a negative correlation between CCT and the discordance of DCT and GAT.
CONCLUSION
The use of GAT correction formulas involves the risk of creating significant error. The correction equations examined showed extensive scatter and resulted in mean IOP values that were lower than the IOP initially measured by GAT. Thus the use of any correction equation may delay diagnosis of glaucoma and should be avoided.
Accurate determination of intraocular pressure (IOP) is essential for correct management of glaucoma. Goldmann applanation tonometry (GAT) is the gold standard for measuring IOP despite its limitations due to its dependence on corneal properties. With the aim of improving the accuracy of GAT readings, several correction formulas have been developed.
OBJECTIVE
The aim of this study was to investigate the accuracy and clinical relevance of five correction equations for GAT.
MATERIAL AND METHODS
Prospective study of 112 glaucoma patients at the University Hospital and Talacker Eye Center, Zurich, Switzerland. The IOP was measured with GAT and dynamic contour tonometry (DCT) in randomized order. The GAT readings were adjusted with five correction equations. The primary study endpoint was the degree of concordance between corrected GAT and DCT readings. A discordance of ≥2 mm Hg was defined as significant. The association between discordant IOP measurements and central corneal thickness (CCT) was the secondary study endpoint.
RESULTS
The mean patient age was 66 ± 13 years (60% females and 56% left eyes). The mean IOP was 17.0 mm Hg for GAT and 20.3 mm Hg for DCT, with a discordance of 3.3 mm Hg between GAT und DCT. The discordances between DCT and the corrected values ranged from 2.7 to 5.4 mm Hg. Spearman's rank testing showed a positive correlation between CCT and the discordances of all correction equations and a negative correlation between CCT and the discordance of DCT and GAT.
CONCLUSION
The use of GAT correction formulas involves the risk of creating significant error. The correction equations examined showed extensive scatter and resulted in mean IOP values that were lower than the IOP initially measured by GAT. Thus the use of any correction equation may delay diagnosis of glaucoma and should be avoided.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1007/s00347-016-0409-3
- PMID 27921133
- Persistent URL
- https://sonar.ch/global/documents/47782
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