Journal article
Multicenter Double-Blind Study Examining the Antidepressant Effectiveness of the Hypericum Extract LI 160
- Hänsgen, K.-D. Institut für Psychologie, Universität Fribourg/Schweiz
- Vesper, J. Fachabteilung für Neurologie und Psychiatrie des Evangelischen Krankenhauses Königin Elisabeth Herzberge, Berlin
- Ploch, M. Lichtwer Pharma GmbH, Berlin, Germany.
- 2017-9-29
Published in:
- Journal of Geriatric Psychiatry and Neurology. - SAGE Publications. - 1994, vol. 7, no. 1_suppl, p. 15-18
English
Seventy-two depressive patients of 11 physicians’ practices were treated in a double-blind study for a period of 6 weeks either with hypericum extract LI 160 or with placebo. Inclusion criterion was a major depression in accordance with DSM-III-R. The changes were assessed using four psychometric scales (HAMD, D-S, BEB, CGI). After 4 weeks of therapy, the statistical evaluation revealed a significant improvement in all four psychometric tests in the active group as compared to the placebo group. After switching the placebo group to active treatment (5th to 6th week of therapy), significant improvements were found in the original placebo group. No serious side effects were observed.
- Language
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- English
- Open access status
- closed
- Identifiers
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- DOI 10.1177/089198879400701s06
- ISSN 0891-9887
- Persistent URL
- https://sonar.ch/global/documents/93149
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