Low incidence of community-acquired pneumonia among human immunodeficiency virus-infected patients after interruption of Pneumocystis carinii pneumonia prophylaxis.
- Eigenmann C Division of Infectious Diseases, University Hospital Berne, Switzerland.
- Flepp M
- Bernasconi E
- Schiffer V
- Telenti A
- Bucher H
- Wagels T
- Egger M
- Furrer H
- 2003-03-26
Published in:
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. - 2003
AIDS-Related Opportunistic Infections
Adult
Aged
Chemoprevention
Community-Acquired Infections
Female
Follow-Up Studies
HIV Infections
Homosexuality, Male
Humans
Incidence
Male
Middle Aged
Pneumonia, Pneumocystis
English
We compared the incidence of bacterial pneumonia among 336 patients who discontinued trimethoprim-sulfamethoxazole (TMP-SMX) as prophylaxis against Pneumocystis carinii pneumonia (PCP) with that among 75 patients who fulfilled the criteria for discontinuation but continued receiving prophylaxis. The difference in the overall incidence rates for the 2 groups (1.2 events per 100 person-years) was not statistically significant. Discontinuation of TMP-SMX prophylaxis against PCP is not associated with a significant increase in the incidence of bacterial pneumonia among patients with a sustained CD4 cell count increase to >200 cells/microL.
- Language
-
- English
- Open access status
- bronze
- Identifiers
-
- DOI 10.1086/368190
- PMID 12652393
- Persistent URL
- https://sonar.ch/global/documents/953
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