Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.
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Kunkle BW
John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA. bkunkle@miami.edu.
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Grenier-Boley B
Inserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.
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Sims R
Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.
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Bis JC
Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.
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Damotte V
Inserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.
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Naj AC
Department of Biostatistics and Epidemiology/Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
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Boland A
Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France.
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Vronskaya M
Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.
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van der Lee SJ
Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
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Amlie-Wolf A
Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
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Bellenguez C
Inserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.
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Frizatti A
Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.
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Chouraki V
Inserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.
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Martin ER
John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
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Sleegers K
Neurodegenerative Brain Diseases Group, Center for Molecular Neurology, VIB, Antwerp, Belgium.
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Badarinarayan N
Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.
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Jakobsdottir J
Icelandic Heart Association, Kopavogur, Iceland.
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Hamilton-Nelson KL
John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
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Moreno-Grau S
Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades-Universitat Internacional de Catalunya, Barcelona, Spain.
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Olaso R
Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France.
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Raybould R
Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.
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Chen Y
Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
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Kuzma AB
Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
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Hiltunen M
Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.
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Morgan T
Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.
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Ahmad S
Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
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Vardarajan BN
Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, NY, USA.
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Epelbaum J
UMR 894, Center for Psychiatry and Neuroscience, Inserm, Université Paris Descartes, Paris, France.
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Hoffmann P
Institute of Human Genetics, University of Bonn, Bonn, Germany.
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Boada M
Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades-Universitat Internacional de Catalunya, Barcelona, Spain.
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Beecham GW
John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
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Garnier JG
Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France.
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Harold D
School of Biotechnology, Dublin City University, Dublin, Ireland.
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Fitzpatrick AL
Department of Family Medicine, University of Washington, Seattle, WA, USA.
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Valladares O
Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
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Moutet ML
Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France.
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Gerrish A
Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.
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Smith AV
Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA.
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Qu L
Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
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Bacq D
Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France.
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Denning N
Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.
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Jian X
Brown Foundation Institute of Molecular Medicine, University of Texas Health Sciences Center at Houston, Houston, TX, USA.
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Zhao Y
Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
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Del Zompo M
Section of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy.
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Fox NC
Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.
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Choi SH
Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades-Universitat Internacional de Catalunya, Barcelona, Spain.
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Mateo I
Neurology Service and CIBERNED, 'Marqués de Valdecilla' University Hospital (University of Cantabria and IDIVAL), Santander, Spain.
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Hughes JT
Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
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Adams HH
Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
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Malamon J
Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
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Sanchez-Garcia F
Department of Immunology, Hospital Universitario Doctor Negrín, Las Palmas de Gran Canaria, Spain.
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Patel Y
Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
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Brody JA
Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.
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Dombroski BA
Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
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Naranjo MCD
Department of Immunology, Hospital Universitario Doctor Negrín, Las Palmas de Gran Canaria, Spain.
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Daniilidou M
Department of Neurology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
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Eiriksdottir G
Icelandic Heart Association, Kopavogur, Iceland.
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Mukherjee S
Department of Medicine, University of Washington, Seattle, WA, USA.
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Wallon D
Normandie University, UNIROUEN, Inserm U1245, and Rouen University Hospital, Department of Neurology, Department of Genetics and CNR-MAJ, Normandy Center for Genomic and Personalized Medicine, Rouen, France.
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Uphill J
Department of Neurodegenerative Disease, MRC Prion Unit at UCL, Institute of Prion Diseases, London, UK.
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Aspelund T
Icelandic Heart Association, Kopavogur, Iceland.
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Cantwell LB
Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
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Garzia F
Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France.
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Galimberti D
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Neurodegenerative Diseases Unit, Milan, Italy.
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Hofer E
Clinical Division of Neurogeriatrics, Department of Neurology, Medical University Graz, Graz, Austria.
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Butkiewicz M
Institute for Computational Biology, Department of Population & Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA.
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Fin B
Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France.
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Scarpini E
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Neurodegenerative Diseases Unit, Milan, Italy.
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Sarnowski C
Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
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Bush WS
Institute for Computational Biology, Department of Population & Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA.
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Meslage S
Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France.
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Kornhuber J
Department of Psychiatry and Psychotherapy, University of Erlangen-Nuremberg, Erlangen, Germany.
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White CC
Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.
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Song Y
Institute for Computational Biology, Department of Population & Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA.
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Barber RC
Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, TX, USA.
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Engelborghs S
Laboratory for Neurochemistry and Behavior, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.
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Sordon S
Department of Psychiatry and Psychotherapy, University Hospital, Saarland, Germany.
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Voijnovic D
Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
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Adams PM
Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA.
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Vandenberghe R
Laboratory for Cognitive Neurology, Department of Neurology, University Hospital and University of Leuven, Leuven, Belgium.
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Mayhaus M
Department of Psychiatry and Psychotherapy, University Hospital, Saarland, Germany.
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Cupples LA
Framingham Heart Study, Framingham, MA, USA.
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Albert MS
Department of Neurology, Johns Hopkins University, Baltimore, MD, USA.
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De Deyn PP
Laboratory for Neurochemistry and Behavior, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.
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Gu W
Department of Psychiatry and Psychotherapy, University Hospital, Saarland, Germany.
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Himali JJ
Framingham Heart Study, Framingham, MA, USA.
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Beekly D
National Alzheimer's Coordinating Center, University of Washington, Seattle, WA, USA.
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Squassina A
Section of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy.
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Hartmann AM
Department of Psychiatry, Martin Luther University Halle-Wittenberg, Halle, Germany.
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Orellana A
Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades-Universitat Internacional de Catalunya, Barcelona, Spain.
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Blacker D
Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA.
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Rodriguez-Rodriguez E
Neurology Service and CIBERNED, 'Marqués de Valdecilla' University Hospital (University of Cantabria and IDIVAL), Santander, Spain.
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Lovestone S
Department of Psychiatry, University of Oxford, Oxford, UK.
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Garcia ME
Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, MD, USA.
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Doody RS
Alzheimer's Disease and Memory Disorders Center, Baylor College of Medicine, Houston, TX, USA.
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Munoz-Fernadez C
Department of Immunology, Hospital Universitario Doctor Negrín, Las Palmas de Gran Canaria, Spain.
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Sussams R
Division of Clinical Neurosciences, School of Medicine, University of Southampton, Southampton, UK.
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Lin H
Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
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Fairchild TJ
Office of Strategy and Measurement, University of North Texas Health Science Center, Fort Worth, TX, USA.
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Benito YA
Department of Immunology, Hospital Universitario Doctor Negrín, Las Palmas de Gran Canaria, Spain.
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Holmes C
Division of Clinical Neurosciences, School of Medicine, University of Southampton, Southampton, UK.
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Karamujić-Čomić H
Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
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Frosch MP
C.S. Kubik Laboratory for Neuropathology, Massachusetts General Hospital, Charlestown, MA, USA.
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Thonberg H
Theme Aging, Unit for Hereditary Dementias, Karolinska University Hospital-Solna, Stockholm, Sweden.
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Maier W
German Center for Neurodegenerative Diseases, Bonn, Germany.
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Roshchupkin G
Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
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Ghetti B
Department of Pathology and Laboratory Medicine, Indiana University, Indianapolis, IN, USA.
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Giedraitis V
Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala, Sweden.
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Kawalia A
Department for Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany.
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Li S
Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
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Huebinger RM
Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA.
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Kilander L
Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala, Sweden.
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Moebus S
Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, University Duisburg-Essen, Essen, Germany.
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Hernández I
Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades-Universitat Internacional de Catalunya, Barcelona, Spain.
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Kamboh MI
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
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Brundin R
Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala, Sweden.
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Turton J
Institute of Genetics, Queen's Medical Centre, University of Nottingham, Nottingham, UK.
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Yang Q
Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
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Katz MJ
Department of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA.
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Concari L
Section of Neuroscience, DIMEC-University of Parma, Parma, Italy.
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Lord J
Institute of Genetics, Queen's Medical Centre, University of Nottingham, Nottingham, UK.
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Beiser AS
Framingham Heart Study, Framingham, MA, USA.
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Keene CD
Department of Pathology, University of Washington, Seattle, WA, USA.
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Helisalmi S
Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.
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Kloszewska I
Elderly and Psychiatric Disorders Department, Medical University of Lodz, Lodz, Poland.
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Kukull WA
Department of Epidemiology, University of Washington, Seattle, WA, USA.
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Koivisto AM
Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.
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Lynch A
Mercer's Institute for Research on Aging, St. James's Hospital and Trinity College, Dublin, Ireland.
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Tarraga L
Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades-Universitat Internacional de Catalunya, Barcelona, Spain.
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Larson EB
Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA.
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Haapasalo A
A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.
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Lawlor B
Mercer's Institute for Research on Aging, St. James's Hospital and Trinity College, Dublin, Ireland.
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Mosley TH
Departments of Medicine, Geriatrics, Gerontology and Neurology, University of Mississippi Medical Center, Jackson, MS, USA.
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Lipton RB
Department of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA.
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Solfrizzi V
Interdisciplinary Department of Medicine, Geriatric Medicine and Memory Unity, University of Bari, Bari, Italy.
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Gill M
Mercer's Institute for Research on Aging, St. James's Hospital and Trinity College, Dublin, Ireland.
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Longstreth WT
Department of Epidemiology, University of Washington, Seattle, WA, USA.
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Montine TJ
Department of Pathology, University of Washington, Seattle, WA, USA.
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Frisardi V
Department of Geriatrics, Center for Aging Brain, University of Bari, Bari, Italy.
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Diez-Fairen M
Fundació per la Recerca Biomèdica i Social Mútua Terrassa, Terrassa, Barcelona, Spain.
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Rivadeneira F
Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
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Petersen RC
Department of Neurology, Mayo Clinic, Rochester, MN, USA.
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Deramecourt V
CHU Lille, Memory Center of Lille (Centre Mémoire de Ressources et de Recherche), Lille, France.
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Alvarez I
Fundació per la Recerca Biomèdica i Social Mútua Terrassa, Terrassa, Barcelona, Spain.
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Salani F
Department of Clinical and Behavioral Neurology, Experimental Neuropsychobiology Laboratory, IRCCS Santa Lucia Foundation, Rome, Italy.
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Ciaramella A
Department of Clinical and Behavioral Neurology, Experimental Neuropsychobiology Laboratory, IRCCS Santa Lucia Foundation, Rome, Italy.
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Boerwinkle E
School of Public Health, Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX, USA.
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Reiman EM
Neurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ, USA.
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Fievet N
Inserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.
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Rotter JI
Institute for Translational Genomics and Population Sciences, Departments of Pediatrics and Medicine, Los Angeles BioMedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA.
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Reisch JS
Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, TX, USA.
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Hanon O
University Paris Descartes, EA 4468, AP-HP, Geriatrics Department, Hôpital Broca, Paris, France.
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Cupidi C
Regional Neurogenetic Centre (CRN), ASP Catanzaro, Lamezia Terme, Italy.
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Andre Uitterlinden AG
Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
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Royall DR
Departments of Psychiatry, Medicine, Family & Community Medicine, South Texas Veterans Health Administration Geriatric Research Education & Clinical Center (GRECC), UT Health Science Center at San Antonio, San Antonio, TX, USA.
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Dufouil C
University of Bordeaux, Inserm 1219, Bordeaux, France.
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Maletta RG
Regional Neurogenetic Centre (CRN), ASP Catanzaro, Lamezia Terme, Italy.
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de Rojas I
Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades-Universitat Internacional de Catalunya, Barcelona, Spain.
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Sano M
Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
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Brice A
Inserm U1127, CNRS UMR 7225, Sorbonne Universités, UPMC Université Paris 06, UMRS 1127, Institut du Cerveau et de la Moelle Épinière, Paris, France.
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Cecchetti R
Section of Gerontology and Geriatrics, Department of Medicine, University of Perugia, Perugia, Italy.
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George-Hyslop PS
Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.
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Ritchie K
Inserm U1061 Neuropsychiatry, La Colombière Hospital, Montpellier, France.
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Tsolaki M
Department of Neurology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
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Tsuang DW
VA Puget Sound Health Care System/>GRECC, Seattle, WA, USA.
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Dubois B
Institut de la Mémoire et de la Maladie d'Alzheimer and Institut du Cerveau et de la Moelle Épinière, Département de Neurologie, Hôpital de la Pitié-Salpêtrière, Paris, France.
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Craig D
Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.
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Wu CK
Departments of Neurology, Pharmacology & Neuroscience, Texas Tech University Health Science Center, Lubbock, TX, USA.
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Soininen H
Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.
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Avramidou D
Department of Neurology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
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Albin RL
Department of Neurology, University of Michigan, Ann Arbor, MI, USA.
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Fratiglioni L
Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.
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Germanou A
Department of Neurology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
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Apostolova LG
Indiana Alzheimer's Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA.
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Keller L
Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.
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Koutroumani M
Department of Neurology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
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Arnold SE
Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
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Panza F
Department of Geriatrics, Center for Aging Brain, University of Bari, Bari, Italy.
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Gkatzima O
Department of Neurology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
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Asthana S
Geriatric Research, Education and Clinical Center (GRECC), University of Wisconsin, Madison, WI, USA.
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Hannequin D
Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
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Whitehead P
John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
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Atwood CS
Department of Medical and Molecular Genetics, Indiana University, Indianapolis, IN, USA.
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Caffarra P
Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh, PA, USA.
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Hampel H
AXA Research Fund & Sorbonne University Chair, Paris, France.
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Quintela I
Grupo de Medicina Xenomica, Universidade de Santiago de Compostela, Centro Nacional de Genotipado, Centro de Investigación Biomédica en Red de Enfermedades Raras, Santiago de Compostela, Spain.
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Carracedo Á
Grupo de Medicina Xenomica, Universidade de Santiago de Compostela, Centro Nacional de Genotipado, Centro de Investigación Biomédica en Red de Enfermedades Raras, Santiago de Compostela, Spain.
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Lannfelt L
Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala, Sweden.
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Rubinsztein DC
Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.
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Barnes LL
Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.
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Pasquier F
CHU Lille, Memory Center of Lille (Centre Mémoire de Ressources et de Recherche), Lille, France.
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Frölich L
Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany.
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Barral S
Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, NY, USA.
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McGuinness B
Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.
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Beach TG
Civin Laboratory for Neuropathology, Banner Sun Health Research Institute, Phoenix, AZ, USA.
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Johnston JA
Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.
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Becker JT
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
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Passmore P
Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.
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Bigio EH
Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
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Schott JM
Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.
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Bird TD
Department of Neurology, University of Washington, Seattle, WA, USA.
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Warren JD
Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.
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Boeve BF
Department of Neurology, Mayo Clinic, Rochester, MN, USA.
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Lupton MK
Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
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Bowen JD
Swedish Medical Center, Seattle, WA, USA.
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Proitsi P
Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
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Boxer A
Department of Neurology, University of California, San Francisco, San Francisco, CA, USA.
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Powell JF
Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
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Burke JR
Department of Neurology, Duke University, Durham, NC, USA.
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Kauwe JSK
Departments of Biology, Brigham Young University, Provo, UT, USA.
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Burns JM
University of Kansas Alzheimer's Disease Center, University of Kansas Medical Center, Kansas City, KS, USA.
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Mancuso M
Department of Experimental and Clinical Medicine, Neurological Institute, University of Pisa, Pisa, Italy.
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Buxbaum JD
Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
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Bonuccelli U
Department of Experimental and Clinical Medicine, Neurological Institute, University of Pisa, Pisa, Italy.
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Cairns NJ
Department of Pathology and Immunology, Washington University, St. Louis, MO, USA.
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McQuillin A
Division of Psychiatry, University College London, London, UK.
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Cao C
USF Health Byrd Alzheimer's Institute, University of South Florida, Tampa, FL, USA.
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Livingston G
Division of Psychiatry, University College London, London, UK.
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Carlson CS
Department of Medicine, University of Wisconsin, Madison, WI, USA.
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Bass NJ
Division of Psychiatry, University College London, London, UK.
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Carlsson CM
Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
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Hardy J
Department of Molecular Neuroscience, UCL, Institute of Neurology, London, UK.
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Carney RM
Mental Health & Behavioral Science Service, Bruce W. Carter VA Medical Center, Miami, FL, USA.
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Bras J
UK Dementia Research Institute at UCL, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.
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Carrasquillo MM
Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.
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Guerreiro R
UK Dementia Research Institute at UCL, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.
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Allen M
Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.
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Chui HC
Department of Neurology, University of Southern California, Los Angeles, CA, USA.
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Fisher E
Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.
-
Masullo C
Department of Neurology, Catholic University of Rome, Rome, Italy.
-
Crocco EA
Department of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, Miami, FL, USA.
-
DeCarli C
Department of Neurology, University of California, Davis, Sacramento, CA, USA.
-
Bisceglio G
Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.
-
Dick M
Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, Irvine, CA, USA.
-
Ma L
Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.
-
Duara R
Wien Center for Alzheimer's Disease and Memory Disorders, Mount Sinai Medical Center, Miami Beach, FL, USA.
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Graff-Radford NR
Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.
-
Evans DA
Rush Institute for Healthy Aging, Department of Internal Medicine, Rush University Medical Center, Chicago, IL, USA.
-
Hodges A
Department of Old Age Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
-
Faber KM
Indiana Alzheimer's Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA.
-
Scherer M
Department of Primary Medical Care, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
-
Fallon KB
Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA.
-
Riemenschneider M
Department of Psychiatry and Psychotherapy, University Hospital, Saarland, Germany.
-
Fardo DW
Sanders-Brown Center on Aging, Department of Biostatistics, University of Kentucky, Lexington, KY, USA.
-
Heun R
Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.
-
Farlow MR
Department of Neurology, Indiana University, Indianapolis, IN, USA.
-
Kölsch H
Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.
-
Ferris S
Department of Psychiatry, New York University, New York, NY, USA.
-
Leber M
Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany.
-
Foroud TM
Indiana Alzheimer's Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA.
-
Heuser I
Department of Psychiatry and Psychotherapy, Charité University Medicine, Berlin, Germany.
-
Galasko DR
Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
-
Giegling I
Department of Psychiatry, Martin Luther University Halle-Wittenberg, Halle, Germany.
-
Gearing M
Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA, USA.
-
Hüll M
Department of Psychiatry, University of Freiburg, Freiburg, Germany.
-
Geschwind DH
Neurogenetics Program, University of California, Los Angeles, Los Angeles, CA, USA.
-
Gilbert JR
John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
-
Morris J
Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.
-
Green RC
Division of Genetics, Department of Medicine and Partners Center for Personalized Genetic Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
-
Mayo K
Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.
-
Growdon JH
Department of Neurology, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.
-
Feulner T
Department of Psychiatry and Psychotherapy, University Hospital, Saarland, Germany.
-
Hamilton RL
Department of Pathology (Neuropathology), University of Pittsburgh, Pittsburgh, PA, USA.
-
Harrell LE
Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA.
-
Drichel D
Cologne Center for Genomics, University of Cologne, Cologne, Germany.
-
Honig LS
Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, NY, USA.
-
Cushion TD
Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.
-
Huentelman MJ
Neurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ, USA.
-
Hollingworth P
Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.
-
Hulette CM
Department of Pathology, Duke University, Durham, NC, USA.
-
Hyman BT
Department of Neurology, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.
-
Marshall R
Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.
-
Jarvik GP
Department of Genome Sciences, University of Washington, Seattle, WA, USA.
-
Meggy A
Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.
-
Abner E
Sanders-Brown Center on Aging, College of Public Health, Department of Epidemiology, University of Kentucky, Lexington, KY, USA.
-
Menzies GE
Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.
-
Jin LW
Unidad Clínica de Enfermedades Infecciosas y Microbiología, Hospital Universitario de Valme, Sevilla, Spain.
-
Leonenko G
Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.
-
Real LM
Unidad Clínica de Enfermedades Infecciosas y Microbiología, Hospital Universitario de Valme, Sevilla, Spain.
-
Jun GR
Department of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, MA, USA.
-
Baldwin CT
Department of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, MA, USA.
-
Grozeva D
Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.
-
Karydas A
Swedish Medical Center, Seattle, WA, USA.
-
Russo G
Functional Genomics Center Zurich, ETH/University of Zurich, Zurich, Switzerland.
-
Kaye JA
Department of Neurology, Oregon Health &Science University, Portland, OR, USA.
-
Kim R
Department of Pathology and Laboratory Medicine, University of California, Irvine, Irvine, CA, USA.
-
Jessen F
German Center for Neurodegenerative Diseases, Bonn, Germany.
-
Kowall NW
Department of Neurology, Boston University School of Medicine, Boston, MA, USA.
-
Vellas B
Inserm U558, University of Toulouse, Toulouse, France.
-
Kramer JH
Department of Neuropsychology, University of California San Francisco, San Francisco, CA, USA.
-
Vardy E
Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, UK.
-
LaFerla FM
Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA, USA.
-
Jöckel KH
Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, University Duisburg-Essen, Essen, Germany.
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Lah JJ
Department of Neurology, Emory University, Atlanta, GA, USA.
-
Dichgans M
Institute for Stroke and Dementia Research, Klinikum der Universität München, Munich, Germany.
-
Leverenz JB
Cleveland Clinic Lou Ruvo Center for Brain Health, Cleveland Clinic, Cleveland, OH, USA.
-
Mann D
Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
-
Levey AI
Department of Neurology, Emory University, Atlanta, GA, USA.
-
Pickering-Brown S
Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
-
Lieberman AP
Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
-
Klopp N
Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Munich, Germany.
-
Lunetta KL
Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
-
Wichmann HE
Helmholtz Center Munich, Institute of Epidemiology, Neuherberg, Munich, Germany.
-
Lyketsos CG
Department of Psychiatry, Johns Hopkins University, Baltimore, MD, USA.
-
Morgan K
Human Genetics, Schools of Life Sciences and Medicine, University of Nottingham, Nottingham, UK.
-
Marson DC
Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA.
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Brown K
Institute of Genetics, Queen's Medical Centre, University of Nottingham, Nottingham, UK.
-
Martiniuk F
Department of Medicine-Pulmonary, New York University, New York, NY, USA.
-
Medway C
Institute of Genetics, Queen's Medical Centre, University of Nottingham, Nottingham, UK.
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Mash DC
Department of Neurology, University of Miami, Miami, FL, USA.
-
Nöthen MM
Institute of Human Genetics, University of Bonn, Bonn, Germany.
-
Masliah E
Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
-
Hooper NM
Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
-
McCormick WC
Department of Medicine, University of Washington, Seattle, WA, USA.
-
Daniele A
Institute of Neurology, Catholic University of Sacred Hearth, Rome, Italy.
-
McCurry SM
School of Nursing Northwest Research Group on Aging, University of Washington, Seattle, WA, USA.
-
Bayer A
Institute of Primary Care and Public Health, Cardiff University, University Hospital of Wales, Cardiff, UK.
-
McDavid AN
USF Health Byrd Alzheimer's Institute, University of South Florida, Tampa, FL, USA.
-
Gallacher J
Department of Psychiatry, University of Oxford, Oxford, UK.
-
McKee AC
Department of Neurology, Boston University School of Medicine, Boston, MA, USA.
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van den Bussche H
Department of Primary Medical Care, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
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Mesulam M
Mesulam Center for Cognitive Neurology and Alzheimer's Disease, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
-
Brayne C
Cambridge Institute of Public Health, University of Cambridge School of Clinical Medicine, Cambridge, UK.
-
Miller BL
Weill Institute for Neurosciences, Memory and Aging Center, University of California, San Francisco, San Francisco, CA, USA.
-
Riedel-Heller S
Institute of Social Medicine, Occupational Health and Public Health, University of Leipzig, Leipzig, Germany.
-
Miller CA
Department of Pathology, University of Southern California, Los Angeles, CA, USA.
-
Miller JW
Department of Pathology and Laboratory Medicine, University of California, Davis, Sacramento, CA, USA.
-
Al-Chalabi A
Institute of Psychiatry, Psychology and Neuroscienceó, King's College London, London, UK.
-
Morris JC
Department of Pathology and Immunology, Washington University, St. Louis, MO, USA.
-
Shaw CE
Institute of Psychiatry, Psychology and Neuroscienceó, King's College London, London, UK.
-
Myers AJ
Department of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, Miami, FL, USA.
-
Wiltfang J
Department of Psychiatry and Psychotherapy, University Medical Center Goettingen, Goettingen, Germany.
-
O'Bryant S
Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, TX, USA.
-
Olichney JM
Department of Neurology, University of California, Davis, Sacramento, CA, USA.
-
Alvarez V
Molecular Genetics Laboratory-Hospital, University of Central Asturias, Oviedo, Spain.
-
Parisi JE
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
-
Singleton AB
Molecular Genetics Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
-
Paulson HL
Department of Neurology, University of Michigan, Ann Arbor, MI, USA.
-
Collinge J
Department of Neurodegenerative Disease, MRC Prion Unit at UCL, Institute of Prion Diseases, London, UK.
-
Perry WR
John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
-
Mead S
Department of Neurodegenerative Disease, MRC Prion Unit at UCL, Institute of Prion Diseases, London, UK.
-
Peskind E
Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, USA.
-
Cribbs DH
Department of Neurology, University of California, Irvine, Irvine, CA, USA.
-
Rossor M
Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.
-
Pierce A
Department of Neurology, University of California, Irvine, Irvine, CA, USA.
-
Ryan NS
Department of Neurodegenerative Disease, MRC Prion Unit at UCL, Institute of Prion Diseases, London, UK.
-
Poon WW
Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, Irvine, CA, USA.
-
Nacmias B
Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.
-
Potter H
Department of Neurology, University of Colorado School of Medicine, Aurora, CO, USA.
-
Sorbi S
Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.
-
Quinn JF
Department of Primary Medical Care, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
-
Sacchinelli E
Department of Clinical and Behavioral Neurology, Experimental Neuropsychobiology Laboratory, IRCCS Santa Lucia Foundation, Rome, Italy.
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Raj A
USF Health Byrd Alzheimer's Institute, University of South Florida, Tampa, FL, USA.
-
Spalletta G
Laboratory of Neuropsychiatry, IRCCS Santa Lucia Foundation, Rome, Italy.
-
Raskind M
Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, USA.
-
Caltagirone C
Laboratory of Neuropsychiatry, IRCCS Santa Lucia Foundation, Rome, Italy.
-
Bossù P
Department of Clinical and Behavioral Neurology, Experimental Neuropsychobiology Laboratory, IRCCS Santa Lucia Foundation, Rome, Italy.
-
Orfei MD
Laboratory of Neuropsychiatry, IRCCS Santa Lucia Foundation, Rome, Italy.
-
Reisberg B
Department of Psychiatry, New York University, New York, NY, USA.
-
Clarke R
Oxford Healthy Aging Project, Clinical Trial Service Unit, University of Oxford, Oxford, UK.
-
Reitz C
Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, NY, USA.
-
Smith AD
Oxford Project to Investigate Memory and Ageing, University of Oxford, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, UK.
-
Ringman JM
Department of Neurology, Keck School of Medicine at the University of Southern California, Los Angeles, Los Angeles, CA, USA.
-
Warden D
Oxford Project to Investigate Memory and Ageing, University of Oxford, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, UK.
-
Roberson ED
Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA.
-
Wilcock G
Oxford Project to Investigate Memory and Ageing, University of Oxford, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, UK.
-
Rogaeva E
Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, Ontario, Canada.
-
Bruni AC
Regional Neurogenetic Centre (CRN), ASP Catanzaro, Lamezia Terme, Italy.
-
Rosen HJ
Department of Neurology, University of California, San Francisco, San Francisco, CA, USA.
-
Gallo M
Regional Neurogenetic Centre (CRN), ASP Catanzaro, Lamezia Terme, Italy.
-
Rosenberg RN
Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
-
Ben-Shlomo Y
Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
-
Sager MA
Department of Medicine, University of Wisconsin, Madison, WI, USA.
-
Mecocci P
Section of Gerontology and Geriatrics, Department of Medicine, University of Perugia, Perugia, Italy.
-
Saykin AJ
Indiana Alzheimer's Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA.
-
Pastor P
Fundació per la Recerca Biomèdica i Social Mútua Terrassa, Terrassa, Barcelona, Spain.
-
Cuccaro ML
John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
-
Vance JM
John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
-
Schneider JA
Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.
-
Schneider LS
Department of Neurology, University of Southern California, Los Angeles, CA, USA.
-
Slifer S
John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
-
Seeley WW
Department of Neurology, University of California, San Francisco, San Francisco, CA, USA.
-
Smith AG
USF Health Byrd Alzheimer's Institute, University of South Florida, Tampa, FL, USA.
-
Sonnen JA
Department of Pathology, University of Washington, Seattle, WA, USA.
-
Spina S
Department of Pathology and Laboratory Medicine, Indiana University, Indianapolis, IN, USA.
-
Stern RA
Department of Neurology, Boston University School of Medicine, Boston, MA, USA.
-
Swerdlow RH
University of Kansas Alzheimer's Disease Center, University of Kansas Medical Center, Kansas City, KS, USA.
-
Tang M
Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
-
Tanzi RE
Department of Neurology, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.
-
Trojanowski JQ
Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
-
Troncoso JC
Department of Pathology, Johns Hopkins University, Baltimore, MD, USA.
-
Van Deerlin VM
Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
-
Van Eldik LJ
Sanders-Brown Center on Aging, Department of Neuroscience, University of Kentucky, Lexington, KY, USA.
-
Vinters HV
Department of Neurology, University of California, Los Angeles, Los Angeles, CA, USA.
-
Vonsattel JP
Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Pathology, Columbia University, New York, NY, USA.
-
Weintraub S
Mesulam Center for Cognitive Neurology and Alzheimer's Disease, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
-
Welsh-Bohmer KA
Department of Neurology, Duke University, Durham, NC, USA.
-
Wilhelmsen KC
Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
-
Williamson J
Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, NY, USA.
-
Wingo TS
Department of Neurology, Emory University, Atlanta, GA, USA.
-
Woltjer RL
Department of Pathology, Oregon Health & Science University, Portland, OR, USA.
-
Wright CB
National Institute of Neurological Disorders and Stroke, Bethesda, MD, USA.
-
Yu CE
Department of Medicine, University of Washington, Seattle, WA, USA.
-
Yu L
Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.
-
Saba Y
Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Division of Molecular Biology and Biochemistry, Medical University Graz, Graz, Austria.
-
Pilotto A
Gerontology and Geriatrics Research Laboratory, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy.
-
Bullido MJ
Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain.
-
Peters O
Department of Psychiatry and Psychotherapy, Charité University Medicine, Berlin, Germany.
-
Crane PK
Department of Medicine, University of Washington, Seattle, WA, USA.
-
Bennett D
Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.
-
Bosco P
Instituto di Ricovero e Cura a Carattere Scientifico, Associazione Oasi Maria Santissima Srl, Troina, Italy.
-
Coto E
Molecular Genetics Laboratory-Hospital, University of Central Asturias, Oviedo, Spain.
-
Boccardi V
Section of Gerontology and Geriatrics, Department of Medicine, University of Perugia, Perugia, Italy.
-
De Jager PL
Center for Translational and Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center, New York, NY, USA.
-
Lleo A
Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain.
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Warner N
Somerset Partnership NHS Trust, Somerset, UK.
-
Lopez OL
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
-
Ingelsson M
Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala, Sweden.
-
Deloukas P
The Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.
-
Cruchaga C
Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.
-
Graff C
Theme Aging, Unit for Hereditary Dementias, Karolinska University Hospital-Solna, Stockholm, Sweden.
-
Gwilliam R
The Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.
-
Fornage M
Brown Foundation Institute of Molecular Medicine, University of Texas Health Sciences Center at Houston, Houston, TX, USA.
-
Goate AM
Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
-
Sanchez-Juan P
Neurology Service and CIBERNED, 'Marqués de Valdecilla' University Hospital (University of Cantabria and IDIVAL), Santander, Spain.
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Kehoe PG
University of Bristol Medical School, Learning & Research level 2, Southmead Hospital, Bristol, UK.
-
Amin N
Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
-
Ertekin-Taner N
Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.
-
Berr C
Inserm U1061 Neuropsychiatry, La Colombière Hospital, Montpellier, France.
-
Debette S
Inserm U1127, CNRS UMR 7225, Sorbonne Universités, UPMC Université Paris 06, UMRS 1127, Institut du Cerveau et de la Moelle Épinière, Paris, France.
-
Love S
University of Bristol Medical School, Learning & Research level 2, Southmead Hospital, Bristol, UK.
-
Launer LJ
Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, MD, USA.
-
Younkin SG
Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.
-
Dartigues JF
Memory Research and Resources Center, CMRR de Bordeaux, Bordeaux, France.
-
Corcoran C
Utah State University, Logan, UT, USA.
-
Ikram MA
Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
-
Dickson DW
Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.
-
Nicolas G
Normandie University, UNIROUEN, Inserm U1245, and Rouen University Hospital, Department of Neurology, Department of Genetics and CNR-MAJ, Normandy Center for Genomic and Personalized Medicine, Rouen, France.
-
Campion D
Normandie University, UNIROUEN, Inserm U1245, and Rouen University Hospital, Department of Neurology, Department of Genetics and CNR-MAJ, Normandy Center for Genomic and Personalized Medicine, Rouen, France.
-
Tschanz J
Utah State University, Logan, UT, USA.
-
Schmidt H
Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Division of Molecular Biology and Biochemistry, Medical University Graz, Graz, Austria.
-
Hakonarson H
Center for Applied Genomics, Children's Hospital of Philadelphia, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
-
Clarimon J
Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain.
-
Munger R
Utah State University, Logan, UT, USA.
-
Schmidt R
Clinical Division of Neurogeriatrics, Department of Neurology, Medical University Graz, Graz, Austria.
-
Farrer LA
Department of Neurology, Boston University School of Medicine, Boston, MA, USA.
-
Van Broeckhoven C
Neurodegenerative Brain Diseases Group, Center for Molecular Neurology, VIB, Antwerp, Belgium.
-
C O'Donovan M
Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.
-
DeStefano AL
Department of Neurology, Boston University School of Medicine, Boston, MA, USA.
-
Jones L
Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.
-
Haines JL
Institute for Computational Biology, Department of Population & Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA.
-
Deleuze JF
Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France.
-
Owen MJ
Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.
-
Gudnason V
Icelandic Heart Association, Kopavogur, Iceland.
-
Mayeux R
Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, NY, USA.
-
Escott-Price V
Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.
-
Psaty BM
Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.
-
Ramirez A
Department for Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany.
-
Wang LS
Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
-
Ruiz A
Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades-Universitat Internacional de Catalunya, Barcelona, Spain.
-
van Duijn CM
Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
-
Holmans PA
Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.
-
Seshadri S
Framingham Heart Study, Framingham, MA, USA.
-
Williams J
Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.
-
Amouyel P
Inserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.
-
Schellenberg GD
Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
-
Lambert JC
Inserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France. jean-charles.lambert@pasteur-lille.fr.
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Pericak-Vance MA
John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA. mpericak@miami.edu.
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Risk for late-onset Alzheimer's disease (LOAD), the most prevalent dementia, is partially driven by genetics. To identify LOAD risk loci, we performed a large genome-wide association meta-analysis of clinically diagnosed LOAD (94,437 individuals). We confirm 20 previous LOAD risk loci and identify five new genome-wide loci (IQCK, ACE, ADAM10, ADAMTS1, and WWOX), two of which (ADAM10, ACE) were identified in a recent genome-wide association (GWAS)-by-familial-proxy of Alzheimer's or dementia. Fine-mapping of the human leukocyte antigen (HLA) region confirms the neurological and immune-mediated disease haplotype HLA-DR15 as a risk factor for LOAD. Pathway analysis implicates immunity, lipid metabolism, tau binding proteins, and amyloid precursor protein (APP) metabolism, showing that genetic variants affecting APP and Aβ processing are associated not only with early-onset autosomal dominant Alzheimer's disease but also with LOAD. Analyses of risk genes and pathways show enrichment for rare variants (P = 1.32 × 10-7), indicating that additional rare variants remain to be identified. We also identify important genetic correlations between LOAD and traits such as family history of dementia and education.
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green
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https://sonar.ch/global/documents/99068
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